Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers

Parasitism during development impairs normal growth and delays the onset of puberty through altered hormone profiles, including insulin-like growth factor one (IGF-1). Asmammary gland development during prepuberty is strongly dependent on IGF-1, we determined if antiparasitic treatment during this s...

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Detalles Bibliográficos
Autores principales: Perri, Adrián Francisco, Mejía, Miguel E., Licoff, Nicolas, Diab, Santiago, Formía, Néstor Fabián, Ornstein, Ana María, Becú de Villalobos, Damasia, Lacau Mengido, Isabel M.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2013
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/104605
https://ri.conicet.gov.ar/11336/1008
Aporte de:
id I19-R120-10915-104605
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Gastrointestinal parasites
Puberty
IGF-1
Mammary development
Dairy heifers
spellingShingle Ciencias Veterinarias
Gastrointestinal parasites
Puberty
IGF-1
Mammary development
Dairy heifers
Perri, Adrián Francisco
Mejía, Miguel E.
Licoff, Nicolas
Diab, Santiago
Formía, Néstor Fabián
Ornstein, Ana María
Becú de Villalobos, Damasia
Lacau Mengido, Isabel M.
Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
topic_facet Ciencias Veterinarias
Gastrointestinal parasites
Puberty
IGF-1
Mammary development
Dairy heifers
description Parasitism during development impairs normal growth and delays the onset of puberty through altered hormone profiles, including insulin-like growth factor one (IGF-1). Asmammary gland development during prepuberty is strongly dependent on IGF-1, we determined if antiparasitic treatment during this stage of growth improved mammary gland development. One group of Holstein heifers was treated monthly, rotationally with antiparasitic drugs from birth to 70 weeks of age, a second group was untreated. Treated heifer calves had between 56% and 65% less EPG counts than untreated ones. Presence of Ostertagia, Cooperia, Haemonchus and Trichostrongylus was demonstrated. Treatment effectively advanced the onset of puberty and increased IGF-1 levels. At 20, 30, 40 and 70 weeks of age biopsies from the mammary gland were taken and histological sections were prepared and stained with hematoxylin–eosin. Pictures were analyzed to compare parenchyma area in relation to total mammary tissue between groups. Mammary samples from treated heifers had higher ratios of parenchyma/total area than untreated ones. As mammary development during prepuberty is crucial for mammary performance during lactation, these results add new evidence to the importance of gastrointestinal parasite control in heifers.
format Articulo
Articulo
author Perri, Adrián Francisco
Mejía, Miguel E.
Licoff, Nicolas
Diab, Santiago
Formía, Néstor Fabián
Ornstein, Ana María
Becú de Villalobos, Damasia
Lacau Mengido, Isabel M.
author_facet Perri, Adrián Francisco
Mejía, Miguel E.
Licoff, Nicolas
Diab, Santiago
Formía, Néstor Fabián
Ornstein, Ana María
Becú de Villalobos, Damasia
Lacau Mengido, Isabel M.
author_sort Perri, Adrián Francisco
title Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
title_short Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
title_full Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
title_fullStr Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
title_full_unstemmed Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
title_sort gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers
publishDate 2013
url http://sedici.unlp.edu.ar/handle/10915/104605
https://ri.conicet.gov.ar/11336/1008
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