Biotransformation of halogenated 2′-deoxyribosides by immobilized lactic acid bacteria

An efficient and green bioprocess is herein reported to obtain halogenated nucleosides by transglycosylation using immobilized lactic acid bacteria (LAB). Lactobacillus animalis ATCC 35046 showed a yield of 95% at 0.5 h to synthesize 5-fluorouracil-2′-deoxyriboside (floxuridine). Calcium alginate wa...

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Detalles Bibliográficos
Autores principales:	Britos, Claudia Noelia, Cappa, Valeria Alejandra, Rivero, Cintia Wanda, Sambeth, Jorge Enrique, Lozano, Mario Enrique, Trelles, Jorge Abel
Formato:	Articulo Preprint
Lenguaje:	Inglés
Publicado:	2012
Materias:	Química Bioquímica Lactic acid bacteria 2´-N-deoxyribosyltransferase Whole-cell immobilization Antitumoral compounds
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/104350 http://hdl.handle.net/11336/36731
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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