Relationship between Ocular Surface Alterations and Concentrations of Aerial Particulate Matter

Purpose: To evaluate ocular surface alterations in two populations at different exposure levels to particulate matter (PM) in their living and work environments. Methods: A cross-sectional study was conducted, including 78 volunteers from Argentina who lived and worked under different pollution lev...

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Autores principales: Gutiérrez, María de los Ángeles, Giuliani, Daniela Silvana, Porta, Atilio Andrés, Andrinolo, Darío
Formato: Articulo
Lenguaje:Inglés
Publicado: 2019
Materias:
Química
Environmental sciences
Ocular Surface
Particulate Matter
Schirmer I Test
Vital Staining
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/100796
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-100796
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Química
Environmental sciences
Ocular Surface
Particulate Matter
Schirmer I Test
Vital Staining
spellingShingle Química
Environmental sciences
Ocular Surface
Particulate Matter
Schirmer I Test
Vital Staining
Gutiérrez, María de los Ángeles
Giuliani, Daniela Silvana
Porta, Atilio Andrés
Andrinolo, Darío
Relationship between Ocular Surface Alterations and Concentrations of Aerial Particulate Matter
topic_facet Química
Environmental sciences
Ocular Surface
Particulate Matter
Schirmer I Test
Vital Staining
description Purpose: To evaluate ocular surface alterations in two populations at different exposure levels to particulate matter (PM) in their living and work environments. Methods: A cross-sectional study was conducted, including 78 volunteers from Argentina who lived and worked under different pollution levels in an urban (U; n = 44) or industrial zone (I; n = 34). Mean exposure level to PM was evaluated. Responses to the Ocular Symptom Disease Index and McMonnies questionnaire were obtained from all subjects. Subsequently, an assessment through the Schirmer I test (ST), slit lamp microscopy, vital staining, and tear breakup time was conducted. Statistical analyses with Chi-square and Bartlett’s tests, as well as Student’s t-tests and principal component analysis (PCA), were performed. Results: Particles of size < 2.5 μm (PM2.5) level was significantly higher in the I group than the U group (P = 0.04). Ocular surface parameters including bulbar redness, eyelid redness, and the degree of vital staining with fluorescein (SF) and lissamine green (SLG) exhibited difference between the groups. With regards to the tear film, statistically significant differences in the ST value and meibomian gland dysfunction between the groups were detected (P = 0.003 and P = 0.02, respectively). Conjunctival SF and SLG, and ST values were identified as factors which could distinguish groups exposed to different PM levels. Conclusion: Subjects exposed to higher levels of PM in the outdoor air presented greater ocular surface alterations. Thus, ST, SF, and SLG values could be used as convenient indicators of adverse health effects due to exposure to air pollution.
format Articulo
Articulo
author Gutiérrez, María de los Ángeles
Giuliani, Daniela Silvana
Porta, Atilio Andrés
Andrinolo, Darío
author_facet Gutiérrez, María de los Ángeles
Giuliani, Daniela Silvana
Porta, Atilio Andrés
Andrinolo, Darío
author_sort Gutiérrez, María de los Ángeles
title Relationship between Ocular Surface Alterations and Concentrations of Aerial Particulate Matter
title_short Relationship between Ocular Surface Alterations and Concentrations of Aerial Particulate Matter
title_full Relationship between Ocular Surface Alterations and Concentrations of Aerial Particulate Matter
title_fullStr Relationship between Ocular Surface Alterations and Concentrations of Aerial Particulate Matter
title_full_unstemmed Relationship between Ocular Surface Alterations and Concentrations of Aerial Particulate Matter
title_sort relationship between ocular surface alterations and concentrations of aerial particulate matter
publishDate 2019
url http://sedici.unlp.edu.ar/handle/10915/100796
work_keys_str_mv AT gutierrezmariadelosangeles relationshipbetweenocularsurfacealterationsandconcentrationsofaerialparticulatematter
AT giulianidanielasilvana relationshipbetweenocularsurfacealterationsandconcentrationsofaerialparticulatematter
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bdutipo_str Repositorios
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