5 aminolevulinate synthase 5-Aminolevulinate Synthetase Animalia Animals Cytochrome P-450 Enzyme Activation Enzyme Induction Erythropoietic protoporphyria Glutathione Heme Oxygenase (Decyclizing) Heme metabolism Hydroxymethylbilane Synthase Isoflurane Liver Mice Mice, Mutant Strains Mus Oxidative Stress Protoporphyria, Erythropoietic animal experiment animal model animal tissue article controlled study cytochrome P450 cytochrome P450 2E1 drug effect drug mechanism enzyme activity erythropoietic protoporphyria