Isoflurane isoflurane 26 nonhuman 26 article 24 mouse 22 animal experiment 20 controlled study 20 enzyme activity 20 Enflurane 18 Mice 18 5 aminolevulinate synthase 16 Animals 16 animal tissue 16 enflurane 16 male 16 5-Aminolevulinate Synthetase 14 anesthesia 14 animal model 14 heme oxygenase 14 Liver 12 heme synthesis 12 porphobilinogen deaminase 12 priority journal 12 Animalia 10 Heme metabolism 10 heme 10 Glutathione 8 Heme 8 Heme Oxygenase (Decyclizing) 8 Male 8