enzyme activity protein function controlled study 78 article 74 priority journal 74 nonhuman 66 protein expression 54 Animals 48 unclassified drug 48 human 36 Humans 34 mouse 34 signal transduction 34 metabolism 32 animal cell 30 Mice 28 animal experiment 28 animal tissue 22 human cell 22 animal model 20 Protein Binding 18 animal 18 genetics 18 protein analysis 18 Cell Line 16 protein binding 16 protein protein interaction 16 protein processing 14 rat 14 Female 12