Article metabolism priority journal controlled study 332 nonhuman 320 Animals 252 animal 252 unclassified drug 162 genetics 158 human 152 animal experiment 148 Humans 142 animal cell 138 female 134 mouse 134 animal tissue 120 drug effects 120 male 120 Female 112 physiology 108 protein expression 108 Male 102 Mice 100 chemistry 98 signal transduction 90 human cell 80 in vitro study 78 enzyme activity 76 adult 74 cytology 66