Animals Anti-Inflammatory Agents, Non-Steroidal Article Autoimmunity CD8+ T lymphocyte Cellular Microenvironment Disease Models, Animal Encephalomyelitis, Autoimmune, Experimental Female Immunophenotyping Indomethacin Mice Models, Biological Myeloid Cells Neoplasms Nitric Oxide Phenotype Reactive Oxygen Species Signal Transduction T lymphocyte subpopulation T-Lymphocyte Subsets Tumor Burden Tumor Microenvironment animal animal cell animal experiment animal model animal tissue antiinflammatory activity antineoplastic activity