controlled study male signal transduction nonhuman 103 Animals 84 priority journal 80 Male 78 article 74 animal experiment 73 mouse 59 animal tissue 57 animal cell 56 metabolism 48 female 45 human 44 animal 41 Signal Transduction 39 Article 36 Mice 36 protein expression 36 Humans 34 animal model 33 Female 29 human cell 29 rat 29 unclassified drug 25 Rats 23 genetics 21 adult 20 physiology 20