controlled study metabolism mouse Animals 307 animal 305 nonhuman 305 Mice 265 animal experiment 210 priority journal 207 Article 190 animal cell 188 animal tissue 146 animal model 140 genetics 136 human 131 Humans 126 protein expression 126 article 123 female 122 physiology 119 male 117 Female 104 unclassified drug 103 drug effects 97 Male 91 signal transduction 88 pathology 80 cytology 76 human cell 73 gene expression regulation 62