Animals 348 animal animal tissue controlled study nonhuman metabolism 274 animal experiment 249 Article 234 priority journal 224 mouse 174 male 172 physiology 164 female 162 animal cell 150 Mice 148 Male 134 Female 130 animal model 118 article 114 drug effects 101 genetics 101 unclassified drug 95 protein expression 88 pathology 73 adult 70 immunohistochemistry 69 drug effect 67 messenger RNA 59 Humans 57 human 57