animal cell controlled study human human cell nonhuman 61 signal transduction priority journal 51 Animals 49 Humans 47 mouse 43 article 39 Mice 33 animal experiment 31 protein expression 29 Signal Transduction 24 male 23 animal 22 animal model 22 unclassified drug 20 Article 18 animal tissue 18 metabolism 18 female 17 Male 15 cell proliferation 14 immunology 14 protein function 14 Female 13 Cell Line, Tumor 12 cytokine production 12