1-Phosphatidylinositol 3-Kinase Animals Breast Neoplasms Cell Line, Tumor Cell Proliferation Cytoplasm DNA binding protein Matrix Metalloproteinase 2 Matrix Metalloproteinase 9 Mice Mitogen-Activated Protein Kinase Kinases Murinae Neoplasm Metastasis Peptide Hydrolases Progestins Receptors, Progesterone Signal Transduction Urinary Plasminogen Activator animal cell animal experiment animal model article breast cancer breast carcinogenesis cancer cell culture cancer model cell growth cell proliferation controlled study cytoplasm