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Article enzyme activity nonhuman 165 controlled study 156 metabolism 136 priority journal 107 Animals 92 animal 92 unclassified drug 79 animal experiment 62 human 62 animal tissue 58 enzymology 57 protein expression 54 chemistry 51 drug effects 50 mouse 50 oxidative stress 48 Humans 44 physiology 42 male 40 female 38 signal transduction 36 superoxide dismutase 36 catalase 34 genetics 34 Mice 32 animal cell 32 glutathione 32 human cell 30