Toxicity, repellency and flushing out in Triatoma infestans (Hemiptera: Reduviidae) exposed to the repellents DEET and IR3535

DEET and IR3535 are insect repellents present worldwide in commercial products; their efficacy has been mainly evaluated in mosquitoes. This study compares the toxicological effects and the behavioral responses induced by both repellents on the blood-sucking bug Triatoma infestans Klug (Hemiptera: R...

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Detalles Bibliográficos
Autores principales: Reynoso, M.M.N., Seccacini, E.A., Calcagno, J.A., Zerba, E.N., Alzogaray, R.A.
Formato: JOUR
Materias:
Blood-sucking bugs
Diethyltoluamide
Ethyl 3-[acetyl(butyl)amino]propanoate
Locomotor activity
ethyl 3 [acetyl(butyl)amino]propanoate
insect repellent
n,n diethyl 3 methylbenzamide
tetramethrin
unclassified drug
aerosol
Article
bioassay
flushing out bioassay
intoxication
lethal dose
molting
nonhuman
repellency bioassay
Triatoma infestans
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_21678359_v2017_n5_p_Reynoso
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_21678359_v2017_n5_p_Reynoso
record_format dspace
spelling todo:paper_21678359_v2017_n5_p_Reynoso2023-10-03T16:39:39Z Toxicity, repellency and flushing out in Triatoma infestans (Hemiptera: Reduviidae) exposed to the repellents DEET and IR3535 Reynoso, M.M.N. Seccacini, E.A. Calcagno, J.A. Zerba, E.N. Alzogaray, R.A. Blood-sucking bugs Diethyltoluamide Ethyl 3-[acetyl(butyl)amino]propanoate Locomotor activity ethyl 3 [acetyl(butyl)amino]propanoate insect repellent n,n diethyl 3 methylbenzamide tetramethrin unclassified drug aerosol Article bioassay flushing out bioassay intoxication lethal dose molting nonhuman repellency bioassay Triatoma infestans DEET and IR3535 are insect repellents present worldwide in commercial products; their efficacy has been mainly evaluated in mosquitoes. This study compares the toxicological effects and the behavioral responses induced by both repellents on the blood-sucking bug Triatoma infestans Klug (Hemiptera: Reduviidae), one of the main vectors of Chagas disease. When applied topically, the Median Lethal Dose (72 h) for DEET was 220.8 μg/insect. Using IR3535, topical application of 500 μg/insect killed no nymphs. The minimum concentration that produced repellency was the same for both compounds: 1,15 μg/cm2. The effect of a mixture DEET:IR3535 1:1 was similar to that of their pure components. Flushing out was assessed in a chamber with a shelter containing groups of ten nymphs. The repellents were aerosolized on the shelter and the number of insects leaving it was recorded for 60 min. During that time, 0.006 g/m3 of the positive control tetramethrin flushed out 76.7% of the nymphs, while 1.76 g/m3 of DEET or IR3535 flushed out 30 and 0%, respectively. The concentrations required for both compounds to produce toxicity or flushing out are too high to have any practical applications. However, they showed a promising repellency. Additional research should be done to evaluate their possible use for personal protection against T. infestans bites. © 2017 Reynoso et al. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_21678359_v2017_n5_p_Reynoso
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Blood-sucking bugs
Diethyltoluamide
Ethyl 3-[acetyl(butyl)amino]propanoate
Locomotor activity
ethyl 3 [acetyl(butyl)amino]propanoate
insect repellent
n,n diethyl 3 methylbenzamide
tetramethrin
unclassified drug
aerosol
Article
bioassay
flushing out bioassay
intoxication
lethal dose
molting
nonhuman
repellency bioassay
Triatoma infestans
spellingShingle Blood-sucking bugs
Diethyltoluamide
Ethyl 3-[acetyl(butyl)amino]propanoate
Locomotor activity
ethyl 3 [acetyl(butyl)amino]propanoate
insect repellent
n,n diethyl 3 methylbenzamide
tetramethrin
unclassified drug
aerosol
Article
bioassay
flushing out bioassay
intoxication
lethal dose
molting
nonhuman
repellency bioassay
Triatoma infestans
Reynoso, M.M.N.
Seccacini, E.A.
Calcagno, J.A.
Zerba, E.N.
Alzogaray, R.A.
Toxicity, repellency and flushing out in Triatoma infestans (Hemiptera: Reduviidae) exposed to the repellents DEET and IR3535
topic_facet Blood-sucking bugs
Diethyltoluamide
Ethyl 3-[acetyl(butyl)amino]propanoate
Locomotor activity
ethyl 3 [acetyl(butyl)amino]propanoate
insect repellent
n,n diethyl 3 methylbenzamide
tetramethrin
unclassified drug
aerosol
Article
bioassay
flushing out bioassay
intoxication
lethal dose
molting
nonhuman
repellency bioassay
Triatoma infestans
description DEET and IR3535 are insect repellents present worldwide in commercial products; their efficacy has been mainly evaluated in mosquitoes. This study compares the toxicological effects and the behavioral responses induced by both repellents on the blood-sucking bug Triatoma infestans Klug (Hemiptera: Reduviidae), one of the main vectors of Chagas disease. When applied topically, the Median Lethal Dose (72 h) for DEET was 220.8 μg/insect. Using IR3535, topical application of 500 μg/insect killed no nymphs. The minimum concentration that produced repellency was the same for both compounds: 1,15 μg/cm2. The effect of a mixture DEET:IR3535 1:1 was similar to that of their pure components. Flushing out was assessed in a chamber with a shelter containing groups of ten nymphs. The repellents were aerosolized on the shelter and the number of insects leaving it was recorded for 60 min. During that time, 0.006 g/m3 of the positive control tetramethrin flushed out 76.7% of the nymphs, while 1.76 g/m3 of DEET or IR3535 flushed out 30 and 0%, respectively. The concentrations required for both compounds to produce toxicity or flushing out are too high to have any practical applications. However, they showed a promising repellency. Additional research should be done to evaluate their possible use for personal protection against T. infestans bites. © 2017 Reynoso et al.
format JOUR
author Reynoso, M.M.N.
Seccacini, E.A.
Calcagno, J.A.
Zerba, E.N.
Alzogaray, R.A.
author_facet Reynoso, M.M.N.
Seccacini, E.A.
Calcagno, J.A.
Zerba, E.N.
Alzogaray, R.A.
author_sort Reynoso, M.M.N.
title Toxicity, repellency and flushing out in Triatoma infestans (Hemiptera: Reduviidae) exposed to the repellents DEET and IR3535
title_short Toxicity, repellency and flushing out in Triatoma infestans (Hemiptera: Reduviidae) exposed to the repellents DEET and IR3535
title_full Toxicity, repellency and flushing out in Triatoma infestans (Hemiptera: Reduviidae) exposed to the repellents DEET and IR3535
title_fullStr Toxicity, repellency and flushing out in Triatoma infestans (Hemiptera: Reduviidae) exposed to the repellents DEET and IR3535
title_full_unstemmed Toxicity, repellency and flushing out in Triatoma infestans (Hemiptera: Reduviidae) exposed to the repellents DEET and IR3535
title_sort toxicity, repellency and flushing out in triatoma infestans (hemiptera: reduviidae) exposed to the repellents deet and ir3535
url http://hdl.handle.net/20.500.12110/paper_21678359_v2017_n5_p_Reynoso
work_keys_str_mv AT reynosommn toxicityrepellencyandflushingoutintriatomainfestanshemipterareduviidaeexposedtotherepellentsdeetandir3535
AT seccaciniea toxicityrepellencyandflushingoutintriatomainfestanshemipterareduviidaeexposedtotherepellentsdeetandir3535
AT calcagnoja toxicityrepellencyandflushingoutintriatomainfestanshemipterareduviidaeexposedtotherepellentsdeetandir3535
AT zerbaen toxicityrepellencyandflushingoutintriatomainfestanshemipterareduviidaeexposedtotherepellentsdeetandir3535
AT alzogarayra toxicityrepellencyandflushingoutintriatomainfestanshemipterareduviidaeexposedtotherepellentsdeetandir3535
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