Long range chromatin organization: A new layer in splicing regulation?
Splicing is a predominantly co-transcriptional process that has been shown to be tightly coupled to transcription. Chromatin structure is a key factor that mediates this functional coupling. In light of recent evidence that shows the importance of higher order chromatin organization in the coordinat...
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_21541264_v5_nAPR_pe28726_GomezAcuna |
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todo:paper_21541264_v5_nAPR_pe28726_GomezAcuna2023-10-03T16:39:27Z Long range chromatin organization: A new layer in splicing regulation? Gómez Acuña, L.I. Kornblihtt, A.R. Alternative splicing Chromatin Coupling between transcription and splicing Long-range chromatin interactions cohesin estradiol receptor heterogeneous nuclear ribonucleoprotein L histone polycomb group protein RNA polymerase II transcription factor CTCF chromatin alternative RNA splicing article chromatin structure DNA methylation DNA template embryonic stem cell enhancer region fibroblast gene activation genetic association globin gene human promoter region regulator gene transcription initiation animal chromatin genetic transcription metabolism RNA splicing Animals Chromatin Humans RNA Splicing Transcription, Genetic Splicing is a predominantly co-transcriptional process that has been shown to be tightly coupled to transcription. Chromatin structure is a key factor that mediates this functional coupling. In light of recent evidence that shows the importance of higher order chromatin organization in the coordination and regulation of gene expression, we discuss here the possible roles of long-range chromatin organization in splicing and alternative splicing regulation. © 2014 Landes Bioscience. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_21541264_v5_nAPR_pe28726_GomezAcuna |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Alternative splicing Chromatin Coupling between transcription and splicing Long-range chromatin interactions cohesin estradiol receptor heterogeneous nuclear ribonucleoprotein L histone polycomb group protein RNA polymerase II transcription factor CTCF chromatin alternative RNA splicing article chromatin structure DNA methylation DNA template embryonic stem cell enhancer region fibroblast gene activation genetic association globin gene human promoter region regulator gene transcription initiation animal chromatin genetic transcription metabolism RNA splicing Animals Chromatin Humans RNA Splicing Transcription, Genetic |
| spellingShingle |
Alternative splicing Chromatin Coupling between transcription and splicing Long-range chromatin interactions cohesin estradiol receptor heterogeneous nuclear ribonucleoprotein L histone polycomb group protein RNA polymerase II transcription factor CTCF chromatin alternative RNA splicing article chromatin structure DNA methylation DNA template embryonic stem cell enhancer region fibroblast gene activation genetic association globin gene human promoter region regulator gene transcription initiation animal chromatin genetic transcription metabolism RNA splicing Animals Chromatin Humans RNA Splicing Transcription, Genetic Gómez Acuña, L.I. Kornblihtt, A.R. Long range chromatin organization: A new layer in splicing regulation? |
| topic_facet |
Alternative splicing Chromatin Coupling between transcription and splicing Long-range chromatin interactions cohesin estradiol receptor heterogeneous nuclear ribonucleoprotein L histone polycomb group protein RNA polymerase II transcription factor CTCF chromatin alternative RNA splicing article chromatin structure DNA methylation DNA template embryonic stem cell enhancer region fibroblast gene activation genetic association globin gene human promoter region regulator gene transcription initiation animal chromatin genetic transcription metabolism RNA splicing Animals Chromatin Humans RNA Splicing Transcription, Genetic |
| description |
Splicing is a predominantly co-transcriptional process that has been shown to be tightly coupled to transcription. Chromatin structure is a key factor that mediates this functional coupling. In light of recent evidence that shows the importance of higher order chromatin organization in the coordination and regulation of gene expression, we discuss here the possible roles of long-range chromatin organization in splicing and alternative splicing regulation. © 2014 Landes Bioscience. |
| format |
JOUR |
| author |
Gómez Acuña, L.I. Kornblihtt, A.R. |
| author_facet |
Gómez Acuña, L.I. Kornblihtt, A.R. |
| author_sort |
Gómez Acuña, L.I. |
| title |
Long range chromatin organization: A new layer in splicing regulation? |
| title_short |
Long range chromatin organization: A new layer in splicing regulation? |
| title_full |
Long range chromatin organization: A new layer in splicing regulation? |
| title_fullStr |
Long range chromatin organization: A new layer in splicing regulation? |
| title_full_unstemmed |
Long range chromatin organization: A new layer in splicing regulation? |
| title_sort |
long range chromatin organization: a new layer in splicing regulation? |
| url |
http://hdl.handle.net/20.500.12110/paper_21541264_v5_nAPR_pe28726_GomezAcuna |
| work_keys_str_mv |
AT gomezacunali longrangechromatinorganizationanewlayerinsplicingregulation AT kornblihttar longrangechromatinorganizationanewlayerinsplicingregulation |
| _version_ |
1807322364846800896 |