Canine oral eosinophilic granuloma treated with electrochemotherapy

A case of a canine oral eosinophilic granuloma in a 14-year-old female crossbred is described.The dog was presented with a history of ptyalism, halitosis, local pain, decreased appetite, and blood staining noted on food and water bowls. Clinical, hematologic, and biochemical examinations, abdominal...

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Autores principales: Tellado, M.N., DiegoMichinski, S., Olaiz, N., Maglietti, F., Marshall, G.
Formato: JOUR
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_20907001_v2014_n_p_Tellado
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spelling todo:paper_20907001_v2014_n_p_Tellado2023-10-03T16:39:21Z Canine oral eosinophilic granuloma treated with electrochemotherapy Tellado, M.N. DiegoMichinski, S. Olaiz, N. Maglietti, F. Marshall, G. A case of a canine oral eosinophilic granuloma in a 14-year-old female crossbred is described.The dog was presented with a history of ptyalism, halitosis, local pain, decreased appetite, and blood staining noted on food and water bowls. Clinical, hematologic, and biochemical examinations, abdominal ultrasonography, and 3-view chest radiographs were performed, and no metastases were found. Histopathologic examination of two 6mm punch biopsies from the oral lesion revealed the presence of eosinophilic granulomatous lesions in the submucosa. After treatment with corticosteroids and wide spectrum antibiotics no significant changes in clinical signs and lesion size were observed. Electrochemotherapy (ECT), a novel tumor treatment routinely used for cutaneous and subcutaneous tumors in human patients in the European Union since 2006, was used to treat the eosinophilic granuloma. The procedurewas performed under general anesthesia, followed by intravenous administration of bleomycin. Sixweeks after treatment a complete response with disappearance of the mass and improvement of clinical signs were observed. © 2014 Matias Nicolás Tellado et al. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_20907001_v2014_n_p_Tellado
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
description A case of a canine oral eosinophilic granuloma in a 14-year-old female crossbred is described.The dog was presented with a history of ptyalism, halitosis, local pain, decreased appetite, and blood staining noted on food and water bowls. Clinical, hematologic, and biochemical examinations, abdominal ultrasonography, and 3-view chest radiographs were performed, and no metastases were found. Histopathologic examination of two 6mm punch biopsies from the oral lesion revealed the presence of eosinophilic granulomatous lesions in the submucosa. After treatment with corticosteroids and wide spectrum antibiotics no significant changes in clinical signs and lesion size were observed. Electrochemotherapy (ECT), a novel tumor treatment routinely used for cutaneous and subcutaneous tumors in human patients in the European Union since 2006, was used to treat the eosinophilic granuloma. The procedurewas performed under general anesthesia, followed by intravenous administration of bleomycin. Sixweeks after treatment a complete response with disappearance of the mass and improvement of clinical signs were observed. © 2014 Matias Nicolás Tellado et al.
format JOUR
author Tellado, M.N.
DiegoMichinski, S.
Olaiz, N.
Maglietti, F.
Marshall, G.
spellingShingle Tellado, M.N.
DiegoMichinski, S.
Olaiz, N.
Maglietti, F.
Marshall, G.
Canine oral eosinophilic granuloma treated with electrochemotherapy
author_facet Tellado, M.N.
DiegoMichinski, S.
Olaiz, N.
Maglietti, F.
Marshall, G.
author_sort Tellado, M.N.
title Canine oral eosinophilic granuloma treated with electrochemotherapy
title_short Canine oral eosinophilic granuloma treated with electrochemotherapy
title_full Canine oral eosinophilic granuloma treated with electrochemotherapy
title_fullStr Canine oral eosinophilic granuloma treated with electrochemotherapy
title_full_unstemmed Canine oral eosinophilic granuloma treated with electrochemotherapy
title_sort canine oral eosinophilic granuloma treated with electrochemotherapy
url http://hdl.handle.net/20.500.12110/paper_20907001_v2014_n_p_Tellado
work_keys_str_mv AT telladomn canineoraleosinophilicgranulomatreatedwithelectrochemotherapy
AT diegomichinskis canineoraleosinophilicgranulomatreatedwithelectrochemotherapy
AT olaizn canineoraleosinophilicgranulomatreatedwithelectrochemotherapy
AT magliettif canineoraleosinophilicgranulomatreatedwithelectrochemotherapy
AT marshallg canineoraleosinophilicgranulomatreatedwithelectrochemotherapy
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