Trypanosoma cruzi coexpressing ornithine decarboxylase and green fluorescence proteins as a tool to study the role of polyamines in chagas disease pathology

Polyamines are essential for Trypanosoma cruzi, the causative agent of Chagas disease. As T. cruzi behaves as a natural auxotrophic organism, it relies on host polyamines biosynthesis. In this paper we obtained a double-transfected T. cruzi parasite that expresses the green fluorescent protein (GFP)...

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Detalles Bibliográficos
Autores principales: Barclay, J.J., Morosi, L.G., Vanrell, M.C., Trejo, E.C., Romano, P.S., Carrillo, C.
Formato: JOUR
Materias:
green fluorescent protein
ornithine
ornithine decarboxylase
polyamine
animal cell
article
auxotrophy
Chagas disease
controlled study
enzyme activity
enzyme kinetics
fluorescence analysis
genetic transfection
nonhuman
parasite survival
parasite transmission
pathogenesis
priority journal
protein expression
Trypanosoma cruzi
Vero cell
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_20900406_v2011_n1_p_Barclay
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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