Serotonin Subsystems Modulate Diverse and Opposite Behavioral Functions

Pioneering work showed that serotonin (5-HT) neurons have the unique capacity to engage in different and opposed aspects of motivated behaviors such as reward and punishment responses. These findings provided strong evidence about the functional heterogeneity of 5-HT neurons, and their possible enga...

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Detalles Bibliográficos
Autores principales: Garcia-Garcia, A.L., Soiza-Reilly, M.
Formato: INPR
Materias:
5-HT
Amygdala
Chemogenetics
Frontal Cortex
Optogenetics
Punishment
Reward
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19487193_v_n_p_GarciaGarcia
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
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spelling todo:paper_19487193_v_n_p_GarciaGarcia2023-10-03T16:37:13Z Serotonin Subsystems Modulate Diverse and Opposite Behavioral Functions Garcia-Garcia, A.L. Soiza-Reilly, M. 5-HT Amygdala Chemogenetics Frontal Cortex Optogenetics Punishment Reward Pioneering work showed that serotonin (5-HT) neurons have the unique capacity to engage in different and opposed aspects of motivated behaviors such as reward and punishment responses. These findings provided strong evidence about the functional heterogeneity of 5-HT neurons, and their possible engagement in multiple and behaviorally distinct neural subsystems. A recent study provides further compelling evidence supporting this notion, in which two ascending 5-HT circuits modulate opposed aspects of motivated behaviors. © 2018 American Chemical Society. INPR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_19487193_v_n_p_GarciaGarcia
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic 5-HT
Amygdala
Chemogenetics
Frontal Cortex
Optogenetics
Punishment
Reward
spellingShingle 5-HT
Amygdala
Chemogenetics
Frontal Cortex
Optogenetics
Punishment
Reward
Garcia-Garcia, A.L.
Soiza-Reilly, M.
Serotonin Subsystems Modulate Diverse and Opposite Behavioral Functions
topic_facet 5-HT
Amygdala
Chemogenetics
Frontal Cortex
Optogenetics
Punishment
Reward
description Pioneering work showed that serotonin (5-HT) neurons have the unique capacity to engage in different and opposed aspects of motivated behaviors such as reward and punishment responses. These findings provided strong evidence about the functional heterogeneity of 5-HT neurons, and their possible engagement in multiple and behaviorally distinct neural subsystems. A recent study provides further compelling evidence supporting this notion, in which two ascending 5-HT circuits modulate opposed aspects of motivated behaviors. © 2018 American Chemical Society.
format INPR
author Garcia-Garcia, A.L.
Soiza-Reilly, M.
author_facet Garcia-Garcia, A.L.
Soiza-Reilly, M.
author_sort Garcia-Garcia, A.L.
title Serotonin Subsystems Modulate Diverse and Opposite Behavioral Functions
title_short Serotonin Subsystems Modulate Diverse and Opposite Behavioral Functions
title_full Serotonin Subsystems Modulate Diverse and Opposite Behavioral Functions
title_fullStr Serotonin Subsystems Modulate Diverse and Opposite Behavioral Functions
title_full_unstemmed Serotonin Subsystems Modulate Diverse and Opposite Behavioral Functions
title_sort serotonin subsystems modulate diverse and opposite behavioral functions
url http://hdl.handle.net/20.500.12110/paper_19487193_v_n_p_GarciaGarcia
work_keys_str_mv AT garciagarciaal serotoninsubsystemsmodulatediverseandoppositebehavioralfunctions
AT soizareillym serotoninsubsystemsmodulatediverseandoppositebehavioralfunctions
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