Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys

It is well known that uninfected mammalian cells contain DNA sequences which are closely related to retroviral genomic segments. However, these sequences seldom (if ever) have been found associated to highly repetitive (satellite) DNA. RPCS is a 348 bp monomer of a major satellite DNA from the South...

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Autores principales: Rossi, M.S., Pesce, C.G., Reig, O.A., Kornblihtt, A.R., Zorzópulos, J.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19401744_v3_n6_p379_Rossi
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spelling todo:paper_19401744_v3_n6_p379_Rossi2023-10-03T16:36:53Z Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys Rossi, M.S. Pesce, C.G. Reig, O.A. Kornblihtt, A.R. Zorzópulos, J. Caviomorph rodents Retroviral LTRs Satellite DNA CCAAT enhancer binding protein CCAAT Enhancer Binding Proteins DNA binding protein DNA Binding Proteins nuclear protein satellite DNA transcription factor transcription factor nuclear factor 1 animal article binding site genetics metabolism molecular genetics nucleotide sequence Retrovirus rodent TATA box Animal Base Sequence Binding Sites CCAAT-Enhancer-Binding Proteins DNA, Satellite DNA-Binding Proteins Molecular Sequence Data Nuclear Proteins Retroviridae Rodentia TATA Box Transcription Factors It is well known that uninfected mammalian cells contain DNA sequences which are closely related to retroviral genomic segments. However, these sequences seldom (if ever) have been found associated to highly repetitive (satellite) DNA. RPCS is a 348 bp monomer of a major satellite DNA from the South American rodents of the genus Ctenomys. It was found that RPCS contains several elements which are typical of the V) region of retroviral LTRs. These elements are: a) a polypurine tract; b) two enhancer core sequences; c) two NF1 binding sites; d) two C/EBP binding sites; e) two CCAAT-motifs; f) a TATA box, and g) two putative polyadenylation motifs. Furthermore, the relative positions of these elements are as in the U, retroviral regions. © 1993 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. Fil:Rossi, M.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Pesce, C.G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Kornblihtt, A.R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_19401744_v3_n6_p379_Rossi
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Caviomorph rodents
Retroviral LTRs
Satellite DNA
CCAAT enhancer binding protein
CCAAT Enhancer Binding Proteins
DNA binding protein
DNA Binding Proteins
nuclear protein
satellite DNA
transcription factor
transcription factor nuclear factor 1
animal
article
binding site
genetics
metabolism
molecular genetics
nucleotide sequence
Retrovirus
rodent
TATA box
Animal
Base Sequence
Binding Sites
CCAAT-Enhancer-Binding Proteins
DNA, Satellite
DNA-Binding Proteins
Molecular Sequence Data
Nuclear Proteins
Retroviridae
Rodentia
TATA Box
Transcription Factors
spellingShingle Caviomorph rodents
Retroviral LTRs
Satellite DNA
CCAAT enhancer binding protein
CCAAT Enhancer Binding Proteins
DNA binding protein
DNA Binding Proteins
nuclear protein
satellite DNA
transcription factor
transcription factor nuclear factor 1
animal
article
binding site
genetics
metabolism
molecular genetics
nucleotide sequence
Retrovirus
rodent
TATA box
Animal
Base Sequence
Binding Sites
CCAAT-Enhancer-Binding Proteins
DNA, Satellite
DNA-Binding Proteins
Molecular Sequence Data
Nuclear Proteins
Retroviridae
Rodentia
TATA Box
Transcription Factors
Rossi, M.S.
Pesce, C.G.
Reig, O.A.
Kornblihtt, A.R.
Zorzópulos, J.
Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys
topic_facet Caviomorph rodents
Retroviral LTRs
Satellite DNA
CCAAT enhancer binding protein
CCAAT Enhancer Binding Proteins
DNA binding protein
DNA Binding Proteins
nuclear protein
satellite DNA
transcription factor
transcription factor nuclear factor 1
animal
article
binding site
genetics
metabolism
molecular genetics
nucleotide sequence
Retrovirus
rodent
TATA box
Animal
Base Sequence
Binding Sites
CCAAT-Enhancer-Binding Proteins
DNA, Satellite
DNA-Binding Proteins
Molecular Sequence Data
Nuclear Proteins
Retroviridae
Rodentia
TATA Box
Transcription Factors
description It is well known that uninfected mammalian cells contain DNA sequences which are closely related to retroviral genomic segments. However, these sequences seldom (if ever) have been found associated to highly repetitive (satellite) DNA. RPCS is a 348 bp monomer of a major satellite DNA from the South American rodents of the genus Ctenomys. It was found that RPCS contains several elements which are typical of the V) region of retroviral LTRs. These elements are: a) a polypurine tract; b) two enhancer core sequences; c) two NF1 binding sites; d) two C/EBP binding sites; e) two CCAAT-motifs; f) a TATA box, and g) two putative polyadenylation motifs. Furthermore, the relative positions of these elements are as in the U, retroviral regions. © 1993 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
format JOUR
author Rossi, M.S.
Pesce, C.G.
Reig, O.A.
Kornblihtt, A.R.
Zorzópulos, J.
author_facet Rossi, M.S.
Pesce, C.G.
Reig, O.A.
Kornblihtt, A.R.
Zorzópulos, J.
author_sort Rossi, M.S.
title Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys
title_short Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys
title_full Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys
title_fullStr Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys
title_full_unstemmed Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys
title_sort retroviral-like features in the monomer of the major satellite dna from the south american rodents of the genus ctenomys
url http://hdl.handle.net/20.500.12110/paper_19401744_v3_n6_p379_Rossi
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