Whole-cell biosensors: Research and patents

In the last ten years several research articles and patents related to the obtaining and uses of whole-cell biosensors (WCB) have been published. Whole-cell sensors, whole-cell biosensors, chemical sensors, integrated sensors and bioreporters (among others) are the main terms used to define a living...

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Autores principales: Fernández, M.R., Bernik, D.L.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_18747647_v3_n3_p138_Fernandez
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spelling todo:paper_18747647_v3_n3_p138_Fernandez2023-10-03T16:34:09Z Whole-cell biosensors: Research and patents Fernández, M.R. Bernik, D.L. Bioreporters Chemical sensors Integrated sensors Living sensors Whole-cell biosensors Whole-cell sensors Bioreporters Integrated sensors Living sensors Whole-cell biosensors Whole-cell sensors Cells Chemical analysis Chemical sensors Cytology Detectors Genetic engineering Machinery Nucleic acids Patents and inventions Biosensors In the last ten years several research articles and patents related to the obtaining and uses of whole-cell biosensors (WCB) have been published. Whole-cell sensors, whole-cell biosensors, chemical sensors, integrated sensors and bioreporters (among others) are the main terms used to define a living cell machinery adapted to detect target analytes at low concentration levels. The methods for constructing and detection technologies for these WCB could be very diverse. Some of them include a foreign nucleic acid sequence to act as reporter, to regulate the reporter's expression or both. But some other inventors exploit the natural properties of organisms without the need of genetic engineering. Another aspect is the localization of the cell at the moment of use. Some inventors, depending on the method of detection, need cells in a special location, such as the surface of a detector, entrapped in a matrix, or in the bulk of the sample. This review intends to compile the most relevant patents related to WCB which enable to illustrate the above mentioned cases of these new types of biosensors. © 2010 Bentham Science Publishers Ltd. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_18747647_v3_n3_p138_Fernandez
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Bioreporters
Chemical sensors
Integrated sensors
Living sensors
Whole-cell biosensors
Whole-cell sensors
Bioreporters
Integrated sensors
Living sensors
Whole-cell biosensors
Whole-cell sensors
Cells
Chemical analysis
Chemical sensors
Cytology
Detectors
Genetic engineering
Machinery
Nucleic acids
Patents and inventions
Biosensors
spellingShingle Bioreporters
Chemical sensors
Integrated sensors
Living sensors
Whole-cell biosensors
Whole-cell sensors
Bioreporters
Integrated sensors
Living sensors
Whole-cell biosensors
Whole-cell sensors
Cells
Chemical analysis
Chemical sensors
Cytology
Detectors
Genetic engineering
Machinery
Nucleic acids
Patents and inventions
Biosensors
Fernández, M.R.
Bernik, D.L.
Whole-cell biosensors: Research and patents
topic_facet Bioreporters
Chemical sensors
Integrated sensors
Living sensors
Whole-cell biosensors
Whole-cell sensors
Bioreporters
Integrated sensors
Living sensors
Whole-cell biosensors
Whole-cell sensors
Cells
Chemical analysis
Chemical sensors
Cytology
Detectors
Genetic engineering
Machinery
Nucleic acids
Patents and inventions
Biosensors
description In the last ten years several research articles and patents related to the obtaining and uses of whole-cell biosensors (WCB) have been published. Whole-cell sensors, whole-cell biosensors, chemical sensors, integrated sensors and bioreporters (among others) are the main terms used to define a living cell machinery adapted to detect target analytes at low concentration levels. The methods for constructing and detection technologies for these WCB could be very diverse. Some of them include a foreign nucleic acid sequence to act as reporter, to regulate the reporter's expression or both. But some other inventors exploit the natural properties of organisms without the need of genetic engineering. Another aspect is the localization of the cell at the moment of use. Some inventors, depending on the method of detection, need cells in a special location, such as the surface of a detector, entrapped in a matrix, or in the bulk of the sample. This review intends to compile the most relevant patents related to WCB which enable to illustrate the above mentioned cases of these new types of biosensors. © 2010 Bentham Science Publishers Ltd.
format JOUR
author Fernández, M.R.
Bernik, D.L.
author_facet Fernández, M.R.
Bernik, D.L.
author_sort Fernández, M.R.
title Whole-cell biosensors: Research and patents
title_short Whole-cell biosensors: Research and patents
title_full Whole-cell biosensors: Research and patents
title_fullStr Whole-cell biosensors: Research and patents
title_full_unstemmed Whole-cell biosensors: Research and patents
title_sort whole-cell biosensors: research and patents
url http://hdl.handle.net/20.500.12110/paper_18747647_v3_n3_p138_Fernandez
work_keys_str_mv AT fernandezmr wholecellbiosensorsresearchandpatents
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