Isolation of three new ent-labdane diterpenes from Dodonaea viscosa Jacquin (Sapindaceae): Preliminary evaluation of antiherpes activity

Investigation of the crude ethanolic extract obtained from the aerial parts of Dodonaea viscosa led to the isolation of three new ent-labdane diterpenes (1-3). The structures were established on the basis of their ESI-MS, UV, IR and NMR spectral data. The crude extract, fractions and compounds were...

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Detalles Bibliográficos
Autores principales: Oliveira, S.Q.D., Almeida, M.T.R.D., Maraslis, F., Silva, I.T., Sincero, T.C.M., Palermo, J.A., Cabrera, G.M., Caro, M.S.B., Simões, C.M.O., Schenkel, E.P.
Formato: JOUR
Materias:
Antiherpes
Diterpenes
Dodonaea viscosa
ent-Labdanes
HSV-1
Sapindaceae
8beta hydroxy 3 o beta dextro glucopyranosyl ent labda 13 en 15,16 diol
antivirus agent
diterpene
ent 15epsilon ethoxylabdan 3alpha,8beta dihydroxy 13(14) en 15,16 olide
ent 16epsilon hydroxylabdan 3alpha,8beta dihydroxy 13(14) en 15,16 olide
plant extract
unclassified drug
antiviral activity
article
carbon nuclear magnetic resonance
drug mechanism
drug structure
electrospray mass spectrometry
Herpes simplex virus 1
heteronuclear multiple bond correlation
heteronuclear single quantum coherence
IC 50
infrared spectroscopy
nonhuman
nuclear Overhauser effect
priority journal
proton nuclear magnetic resonance
ultraviolet spectroscopy
Human herpesvirus 1
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_18743900_v5_n3_p500_Oliveira
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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