Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties

Hyaluronic acid (HA) hydrogels were structured in the form of porous monoliths by means of the ice-segregation-induced self-assembly (ISISA) method coupled with freeze-drying. Physical and chemical parameters were explored in order to fine-tune the microstructure and the incidence on both swelling a...

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Autores principales:	Minaberry, Y., Chiappetta, D.A., Sosnik, A., Jobbágy, M.
Formato:	JOUR
Materias:	Aqueous media Dissolution behavior Drug release properties Hyaluronic acids Physical and chemical parameters Porous monoliths Scanning electron microscopy Thermoanalysis Organic acids gentamicin hyaluronic acid article chemical structure drug release extracellular matrix freeze drying hydrogel physical parameters priority journal scanning electron microscopy thermal analysis tuned swelling Drug Carriers Gentamicins Hyaluronic Acid Hydrogels Microspheres Nanostructures
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_15257797_v14_n1_p1_Minaberry
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_15257797_v14_n1_p1_Minaberry
record_format	dspace
spelling	todo:paper_15257797_v14_n1_p1_Minaberry2023-10-03T16:21:05Z Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties Minaberry, Y. Chiappetta, D.A. Sosnik, A. Jobbágy, M. Aqueous media Dissolution behavior Drug release properties Hyaluronic acids Physical and chemical parameters Porous monoliths Scanning electron microscopy Thermoanalysis Organic acids gentamicin hyaluronic acid article chemical structure drug release extracellular matrix freeze drying hydrogel physical parameters priority journal scanning electron microscopy thermal analysis tuned swelling Drug Carriers Gentamicins Hyaluronic Acid Hydrogels Microspheres Nanostructures Hyaluronic acid (HA) hydrogels were structured in the form of porous monoliths by means of the ice-segregation-induced self-assembly (ISISA) method coupled with freeze-drying. Physical and chemical parameters were explored in order to fine-tune the microstructure and the incidence on both swelling and dissolution behavior in aqueous media. Gentamicin-loaded HA matrices with tuned drug release properties were also prepared; their inherent properties and behavior in solution are discussed in the framework of thermal analysis and scanning electron microscopy inspection. © 2012 American Chemical Society. Fil:Minaberry, Y. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Jobbágy, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_15257797_v14_n1_p1_Minaberry
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Aqueous media Dissolution behavior Drug release properties Hyaluronic acids Physical and chemical parameters Porous monoliths Scanning electron microscopy Thermoanalysis Organic acids gentamicin hyaluronic acid article chemical structure drug release extracellular matrix freeze drying hydrogel physical parameters priority journal scanning electron microscopy thermal analysis tuned swelling Drug Carriers Gentamicins Hyaluronic Acid Hydrogels Microspheres Nanostructures
spellingShingle	Aqueous media Dissolution behavior Drug release properties Hyaluronic acids Physical and chemical parameters Porous monoliths Scanning electron microscopy Thermoanalysis Organic acids gentamicin hyaluronic acid article chemical structure drug release extracellular matrix freeze drying hydrogel physical parameters priority journal scanning electron microscopy thermal analysis tuned swelling Drug Carriers Gentamicins Hyaluronic Acid Hydrogels Microspheres Nanostructures Minaberry, Y. Chiappetta, D.A. Sosnik, A. Jobbágy, M. Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
topic_facet	Aqueous media Dissolution behavior Drug release properties Hyaluronic acids Physical and chemical parameters Porous monoliths Scanning electron microscopy Thermoanalysis Organic acids gentamicin hyaluronic acid article chemical structure drug release extracellular matrix freeze drying hydrogel physical parameters priority journal scanning electron microscopy thermal analysis tuned swelling Drug Carriers Gentamicins Hyaluronic Acid Hydrogels Microspheres Nanostructures
description	Hyaluronic acid (HA) hydrogels were structured in the form of porous monoliths by means of the ice-segregation-induced self-assembly (ISISA) method coupled with freeze-drying. Physical and chemical parameters were explored in order to fine-tune the microstructure and the incidence on both swelling and dissolution behavior in aqueous media. Gentamicin-loaded HA matrices with tuned drug release properties were also prepared; their inherent properties and behavior in solution are discussed in the framework of thermal analysis and scanning electron microscopy inspection. © 2012 American Chemical Society.
format	JOUR
author	Minaberry, Y. Chiappetta, D.A. Sosnik, A. Jobbágy, M.
author_facet	Minaberry, Y. Chiappetta, D.A. Sosnik, A. Jobbágy, M.
author_sort	Minaberry, Y.
title	Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
title_short	Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
title_full	Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
title_fullStr	Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
title_full_unstemmed	Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
title_sort	micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
url	http://hdl.handle.net/20.500.12110/paper_15257797_v14_n1_p1_Minaberry
work_keys_str_mv	AT minaberryy micronanostructuredhyaluronicacidmatriceswithtunedswellinganddrugreleaseproperties AT chiappettada micronanostructuredhyaluronicacidmatriceswithtunedswellinganddrugreleaseproperties AT sosnika micronanostructuredhyaluronicacidmatriceswithtunedswellinganddrugreleaseproperties AT jobbagym micronanostructuredhyaluronicacidmatriceswithtunedswellinganddrugreleaseproperties
_version_	1807318974598217728

Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties

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