Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T

In this study a novel ligand with three carboxylic groups (H3L1) was synthesized. Its non-ion complex with GdL1 holding promise of magnetic resonance imaging (MRI) was synthesized, and the relaxivity of the complex determined. The relaxivity of GdL1 (R1 = 4.5 Mmol- 1•s-1) was larger than that of Gd(...

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Autores principales:	Martínez, M.D., Rustoy, E.M., Raggio, N., Burton, G.
Formato:	JOUR
Materias:	Contrast agent Gadolinium Macrocycle Magnetic resonance imaging Relaxivity
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_13877003_v51_n_p110_Martinez
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_13877003_v51_n_p110_Martinez
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spelling	todo:paper_13877003_v51_n_p110_Martinez2023-10-03T16:12:33Z Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T Martínez, M.D. Rustoy, E.M. Raggio, N. Burton, G. Contrast agent Gadolinium Macrocycle Magnetic resonance imaging Relaxivity In this study a novel ligand with three carboxylic groups (H3L1) was synthesized. Its non-ion complex with GdL1 holding promise of magnetic resonance imaging (MRI) was synthesized, and the relaxivity of the complex determined. The relaxivity of GdL1 (R1 = 4.5 Mmol- 1•s-1) was larger than that of Gd(DTPA)2-(R1 = 3.9 Mmol- 1•s-1). The results showed that the non-ion complex is a prospective MRI contrast agent. © 2014 Elsevier B.V. All rights reserved. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_13877003_v51_n_p110_Martinez
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Contrast agent Gadolinium Macrocycle Magnetic resonance imaging Relaxivity
spellingShingle	Contrast agent Gadolinium Macrocycle Magnetic resonance imaging Relaxivity Martínez, M.D. Rustoy, E.M. Raggio, N. Burton, G. Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T
topic_facet	Contrast agent Gadolinium Macrocycle Magnetic resonance imaging Relaxivity
description	In this study a novel ligand with three carboxylic groups (H3L1) was synthesized. Its non-ion complex with GdL1 holding promise of magnetic resonance imaging (MRI) was synthesized, and the relaxivity of the complex determined. The relaxivity of GdL1 (R1 = 4.5 Mmol- 1•s-1) was larger than that of Gd(DTPA)2-(R1 = 3.9 Mmol- 1•s-1). The results showed that the non-ion complex is a prospective MRI contrast agent. © 2014 Elsevier B.V. All rights reserved.
format	JOUR
author	Martínez, M.D. Rustoy, E.M. Raggio, N. Burton, G.
author_facet	Martínez, M.D. Rustoy, E.M. Raggio, N. Burton, G.
author_sort	Martínez, M.D.
title	Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T
title_short	Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T
title_full	Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T
title_fullStr	Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T
title_full_unstemmed	Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T
title_sort	synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. in vitro relaxivity studies at 0.2 t
url	http://hdl.handle.net/20.500.12110/paper_13877003_v51_n_p110_Martinez
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Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T

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