Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation

A semisynthetic β-glucosidase inhibitor was identified from a chemically engineered extract prepared by reaction with benzenesulfonyl chloride. The structure includes a natural histamine portion and a benzenesulfonyl portion introduced during the diversification step. © 2011 Springer Science+Busines...

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Autores principales: Salazar, M.O., Micheloni, O., Escalante, A.M., Furlan, R.L.E.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_13811991_v15_n3_p713_Salazar
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spelling todo:paper_13811991_v15_n3_p713_Salazar2023-10-03T16:11:47Z Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation Salazar, M.O. Micheloni, O. Escalante, A.M. Furlan, R.L.E. Biomolecular properties Chemically engineered extract Sulfonylation benzene beta glucosidase chloride article chemical engineering chemical reaction chemical structure priority journal synthesis beta-Glucosidase Chemical Engineering Enzyme Inhibitors Molecular Structure Nuclear Magnetic Resonance, Biomolecular Plant Extracts Sulfones Urticaceae A semisynthetic β-glucosidase inhibitor was identified from a chemically engineered extract prepared by reaction with benzenesulfonyl chloride. The structure includes a natural histamine portion and a benzenesulfonyl portion introduced during the diversification step. © 2011 Springer Science+Business Media B.V. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_13811991_v15_n3_p713_Salazar
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Biomolecular properties
Chemically engineered extract
Sulfonylation
benzene
beta glucosidase
chloride
article
chemical engineering
chemical reaction
chemical structure
priority journal
synthesis
beta-Glucosidase
Chemical Engineering
Enzyme Inhibitors
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plant Extracts
Sulfones
Urticaceae
spellingShingle Biomolecular properties
Chemically engineered extract
Sulfonylation
benzene
beta glucosidase
chloride
article
chemical engineering
chemical reaction
chemical structure
priority journal
synthesis
beta-Glucosidase
Chemical Engineering
Enzyme Inhibitors
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plant Extracts
Sulfones
Urticaceae
Salazar, M.O.
Micheloni, O.
Escalante, A.M.
Furlan, R.L.E.
Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation
topic_facet Biomolecular properties
Chemically engineered extract
Sulfonylation
benzene
beta glucosidase
chloride
article
chemical engineering
chemical reaction
chemical structure
priority journal
synthesis
beta-Glucosidase
Chemical Engineering
Enzyme Inhibitors
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plant Extracts
Sulfones
Urticaceae
description A semisynthetic β-glucosidase inhibitor was identified from a chemically engineered extract prepared by reaction with benzenesulfonyl chloride. The structure includes a natural histamine portion and a benzenesulfonyl portion introduced during the diversification step. © 2011 Springer Science+Business Media B.V.
format JOUR
author Salazar, M.O.
Micheloni, O.
Escalante, A.M.
Furlan, R.L.E.
author_facet Salazar, M.O.
Micheloni, O.
Escalante, A.M.
Furlan, R.L.E.
author_sort Salazar, M.O.
title Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation
title_short Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation
title_full Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation
title_fullStr Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation
title_full_unstemmed Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation
title_sort discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation
url http://hdl.handle.net/20.500.12110/paper_13811991_v15_n3_p713_Salazar
work_keys_str_mv AT salazarmo discoveryofabglucosidaseinhibitorfromachemicallyengineeredextractpreparedthroughsulfonylation
AT michelonio discoveryofabglucosidaseinhibitorfromachemicallyengineeredextractpreparedthroughsulfonylation
AT escalanteam discoveryofabglucosidaseinhibitorfromachemicallyengineeredextractpreparedthroughsulfonylation
AT furlanrle discoveryofabglucosidaseinhibitorfromachemicallyengineeredextractpreparedthroughsulfonylation
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