Updating contextual information during consolidation as result of a new memory trace
Reconsolidation studies have led to the hypothesis that memory, when labile, would be modified in order to incorporate new information. This view has reinstated original propositions suggesting that short-term memory provides the organism with an opportunity to evaluate and rearrange information bef...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_10747427_v93_n4_p561_Suarez |
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todo:paper_10747427_v93_n4_p561_Suarez2023-10-03T16:03:07Z Updating contextual information during consolidation as result of a new memory trace Suárez, L.D. Smal, L. Delorenzi, A. Consolidation Memory update Reconsolidation Short-term memory cycloheximide adult animal animal experiment article associative memory behavior controlled study crab escape behavior information long term memory male memory consolidation nonhuman protein synthesis short term memory Amnesia, Retrograde Analysis of Variance Animals Association Learning Brachyura Conditioning, Classical Cycloheximide Environment Freezing Reaction, Cataleptic Male Memory Memory, Short-Term Neuropsychological Tests Protein Synthesis Inhibitors Time Factors Reconsolidation studies have led to the hypothesis that memory, when labile, would be modified in order to incorporate new information. This view has reinstated original propositions suggesting that short-term memory provides the organism with an opportunity to evaluate and rearrange information before storing it, since it is concurrent with the labile state of consolidation. The Chasmagnathus associative memory model is used here to test whether during consolidation it is possible to change some attribute of recently acquired memories. In addition, it is tested whether these changes in behavioral memory features can be explained as modifications on the consolidating memory trace or as a consequence of a new memory trace. We show that short-term memory is, unlike long-term memory, not context specific. During this short period after learning, behavioral memory can be updated in order to incorporate new contextual information. We found that, during this period, the cycloheximide retrograde amnesic effect can be reverted by a single trial in a new context. Finally, by means of memory sensitivity to cycloheximide during consolidation and reconsolidation, we show that the learning of a new context (CS) during this short-term memory period builds up a new memory trace that sustains the behavioral memory update. © 2010 Elsevier Inc. Fil:Suárez, L.D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Delorenzi, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_10747427_v93_n4_p561_Suarez |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Consolidation Memory update Reconsolidation Short-term memory cycloheximide adult animal animal experiment article associative memory behavior controlled study crab escape behavior information long term memory male memory consolidation nonhuman protein synthesis short term memory Amnesia, Retrograde Analysis of Variance Animals Association Learning Brachyura Conditioning, Classical Cycloheximide Environment Freezing Reaction, Cataleptic Male Memory Memory, Short-Term Neuropsychological Tests Protein Synthesis Inhibitors Time Factors |
| spellingShingle |
Consolidation Memory update Reconsolidation Short-term memory cycloheximide adult animal animal experiment article associative memory behavior controlled study crab escape behavior information long term memory male memory consolidation nonhuman protein synthesis short term memory Amnesia, Retrograde Analysis of Variance Animals Association Learning Brachyura Conditioning, Classical Cycloheximide Environment Freezing Reaction, Cataleptic Male Memory Memory, Short-Term Neuropsychological Tests Protein Synthesis Inhibitors Time Factors Suárez, L.D. Smal, L. Delorenzi, A. Updating contextual information during consolidation as result of a new memory trace |
| topic_facet |
Consolidation Memory update Reconsolidation Short-term memory cycloheximide adult animal animal experiment article associative memory behavior controlled study crab escape behavior information long term memory male memory consolidation nonhuman protein synthesis short term memory Amnesia, Retrograde Analysis of Variance Animals Association Learning Brachyura Conditioning, Classical Cycloheximide Environment Freezing Reaction, Cataleptic Male Memory Memory, Short-Term Neuropsychological Tests Protein Synthesis Inhibitors Time Factors |
| description |
Reconsolidation studies have led to the hypothesis that memory, when labile, would be modified in order to incorporate new information. This view has reinstated original propositions suggesting that short-term memory provides the organism with an opportunity to evaluate and rearrange information before storing it, since it is concurrent with the labile state of consolidation. The Chasmagnathus associative memory model is used here to test whether during consolidation it is possible to change some attribute of recently acquired memories. In addition, it is tested whether these changes in behavioral memory features can be explained as modifications on the consolidating memory trace or as a consequence of a new memory trace. We show that short-term memory is, unlike long-term memory, not context specific. During this short period after learning, behavioral memory can be updated in order to incorporate new contextual information. We found that, during this period, the cycloheximide retrograde amnesic effect can be reverted by a single trial in a new context. Finally, by means of memory sensitivity to cycloheximide during consolidation and reconsolidation, we show that the learning of a new context (CS) during this short-term memory period builds up a new memory trace that sustains the behavioral memory update. © 2010 Elsevier Inc. |
| format |
JOUR |
| author |
Suárez, L.D. Smal, L. Delorenzi, A. |
| author_facet |
Suárez, L.D. Smal, L. Delorenzi, A. |
| author_sort |
Suárez, L.D. |
| title |
Updating contextual information during consolidation as result of a new memory trace |
| title_short |
Updating contextual information during consolidation as result of a new memory trace |
| title_full |
Updating contextual information during consolidation as result of a new memory trace |
| title_fullStr |
Updating contextual information during consolidation as result of a new memory trace |
| title_full_unstemmed |
Updating contextual information during consolidation as result of a new memory trace |
| title_sort |
updating contextual information during consolidation as result of a new memory trace |
| url |
http://hdl.handle.net/20.500.12110/paper_10747427_v93_n4_p561_Suarez |
| work_keys_str_mv |
AT suarezld updatingcontextualinformationduringconsolidationasresultofanewmemorytrace AT small updatingcontextualinformationduringconsolidationasresultofanewmemorytrace AT delorenzia updatingcontextualinformationduringconsolidationasresultofanewmemorytrace |
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