Correlation between gel structural properties and drug release pattern in scleroglucan matrices

The drug delivery behavior of scleroglucan hydrogels was correlated with the structural features found by means of steady-state fluorescence studies. Theophylline at 0.4 % in weight was used as the model drug and its release was measured using a Franz cell device. The results were fitted with a semi...

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Detalles Bibliográficos
Autores principales: Daraio, M.E., François, N., Bernik, D.L.
Formato: JOUR
Materias:
Drug Release
Fluorescent Molecular Probes
Hydrophilic Matrices
Scleroglucan
scleroglucan
theophylline
analytic method
article
chemical model
correlation analysis
drug delivery system
drug release
empiricism
fluorescence analysis
hydrogel
kinetics
mathematical analysis
microenvironment
molecular probe
priority journal
steady state
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_10717544_v10_n2_p79_Daraio
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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