Robustness of the hypoxic response: Another job for miRNAs?

Living organisms are constantly exposed to environmental and genetic perturbations. Biological robustness enables these organisms to maintain their functional stability in the presence of external or internal changes. It has been proposed that microRNAs (miRNAs), small non-coding regulatory RNAs, co...

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Detalles Bibliográficos
Autores principales: De Lella Ezcurra, A.L., Bertolin, A.P., Melani, M., Wappner, P.
Formato: JOUR
Materias:
Angiogenesis
Hypoxia
Hypoxia-inducible factor
MicroRNAs
Robustness
hypoxia inducible factor 1
hypoxia inducible factor 1alpha
messenger RNA
microRNA
RNA induced silencing complex
RNA polymerase II
3' untranslated region
angiogenesis
article
biology
development
gene expression
genetic variability
human
hypoxia
negative feedback
nonhuman
phenotype
physiology
positive feedback
priority journal
RNA structure
Animals
Anoxia
Humans
Neovascularization, Physiologic
Stress, Physiological
Transcription Factors
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_10588388_v241_n12_p1842_DeLellaEzcurra
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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