Comment on "binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach"

The present manuscript is a comment on the article entitled "Binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach" by Sarita Sarkar and Kakali Bhadra (2014) [1]. In their article, the authors reported the chemical structure as well as the absorption spectra of harma...

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Detalles Bibliográficos
Autores principales:	Alomar, M.L., Micaela Gonzalez, M., Erra-Balsells, R., Cabrerizo, F.M.
Formato:	JOUR
Materias:	Acid-base equilibria Harmalol β-carbolines DNA harmalol harmaline absorption acid base balance article calorimetry chemical structure DNA binding interactions with DNA pH photochemistry priority journal Harmaline
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_10111344_v136_n_p26_Alomar
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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spelling	todo:paper_10111344_v136_n_p26_Alomar2023-10-03T15:56:11Z Comment on "binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach" Alomar, M.L. Micaela Gonzalez, M. Erra-Balsells, R. Cabrerizo, F.M. Acid-base equilibria Harmalol β-carbolines DNA harmalol DNA harmaline absorption acid base balance article calorimetry chemical structure DNA binding interactions with DNA pH photochemistry priority journal DNA Harmaline The present manuscript is a comment on the article entitled "Binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach" by Sarita Sarkar and Kakali Bhadra (2014) [1]. In their article, the authors reported the chemical structure as well as the absorption spectra of harmalol at different pH. On the bases of the previous publications and our own present results, the assignment of the number of the acid-base species and the corresponding pKa values, as well as the chemical structure for each species are erroneous. These facts have strong effect on the conclusions reached by the authors, in terms of the interaction with DNA. © 2014 Elsevier B.V. All rights reserved. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_10111344_v136_n_p26_Alomar
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Acid-base equilibria Harmalol β-carbolines DNA harmalol DNA harmaline absorption acid base balance article calorimetry chemical structure DNA binding interactions with DNA pH photochemistry priority journal DNA Harmaline
spellingShingle	Acid-base equilibria Harmalol β-carbolines DNA harmalol DNA harmaline absorption acid base balance article calorimetry chemical structure DNA binding interactions with DNA pH photochemistry priority journal DNA Harmaline Alomar, M.L. Micaela Gonzalez, M. Erra-Balsells, R. Cabrerizo, F.M. Comment on "binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach"
topic_facet	Acid-base equilibria Harmalol β-carbolines DNA harmalol DNA harmaline absorption acid base balance article calorimetry chemical structure DNA binding interactions with DNA pH photochemistry priority journal DNA Harmaline
description	The present manuscript is a comment on the article entitled "Binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach" by Sarita Sarkar and Kakali Bhadra (2014) [1]. In their article, the authors reported the chemical structure as well as the absorption spectra of harmalol at different pH. On the bases of the previous publications and our own present results, the assignment of the number of the acid-base species and the corresponding pKa values, as well as the chemical structure for each species are erroneous. These facts have strong effect on the conclusions reached by the authors, in terms of the interaction with DNA. © 2014 Elsevier B.V. All rights reserved.
format	JOUR
author	Alomar, M.L. Micaela Gonzalez, M. Erra-Balsells, R. Cabrerizo, F.M.
author_facet	Alomar, M.L. Micaela Gonzalez, M. Erra-Balsells, R. Cabrerizo, F.M.
author_sort	Alomar, M.L.
title	Comment on "binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach"
title_short	Comment on "binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach"
title_full	Comment on "binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach"
title_fullStr	Comment on "binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach"
title_full_unstemmed	Comment on "binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach"
title_sort	comment on "binding of alkaloid harmalol to dna: photophysical and calorimetric approach"
url	http://hdl.handle.net/20.500.12110/paper_10111344_v136_n_p26_Alomar
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_version_	1807316431804563456

Comment on "binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach"

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