Galectin-1 as an Emerging Mediator of Cardiovascular Inflammation: Mechanisms and Therapeutic Opportunities

Galectin-1 (Gal-1), an evolutionarily conserved β-galactoside-binding lectin, controls immune cell homeostasis and tempers acute and chronic inflammation by blunting proinflammatory cytokine synthesis, engaging T-cell apoptotic programs, promoting expansion of T regulatory (Treg) cells, and deactiva...

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Detalles Bibliográficos
Autores principales: Seropian, I.M., González, G.E., Maller, S.M., Berrocal, D.H., Abbate, A., Rabinovich, G.A.
Formato: JOUR
Materias:
ecalectin
galectin
galectin 1
galectin 12
glycan
unclassified drug
vasculotropin receptor
vasculotropin A
acute heart infarction
antiinflammatory activity
atherosclerosis
brain ischemia
cell differentiation
cell expansion
cell survival
Chagas cardiomyopathy
cytokine production
heart failure
immunocompetent cell
mediator
pulmonary hypertension
regulatory T lymphocyte
Review
animal
homeostasis
human
inflammation
metabolism
physiology
Animals
Galectin 1
Homeostasis
Humans
Inflammation
T-Lymphocytes, Regulatory
Vascular Endothelial Growth Factor A
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_09629351_v2018_n_p_Seropian
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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