Gene silencing: Small RNAs control RNA polymerase II elongation

Short interfering RNAs trigger histone silencing marks and stalling of RNA polymerase II at their genomic target sites through a mechanism termed transcriptional gene silencing (TGS). The Argonaute protein NRDE-3, along with NRDE-2, are needed for TGS in C. elegans. TGS also inhibits elongation and...

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Detalles Bibliográficos
Autores principales:	Alló, M., Kornblihtt, A.R.
Formato:	JOUR
Materias:	RNA polymerase II small interfering RNA animal article Caenorhabditis elegans enzymology gene silencing genetic transcription genetics metabolism physiology Animals Gene Silencing RNA Polymerase II RNA, Small Interfering Transcription, Genetic Mammalia
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_09609822_v20_n17_pR704_Allo
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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