Gene silencing: Small RNAs control RNA polymerase II elongation
Short interfering RNAs trigger histone silencing marks and stalling of RNA polymerase II at their genomic target sites through a mechanism termed transcriptional gene silencing (TGS). The Argonaute protein NRDE-3, along with NRDE-2, are needed for TGS in C. elegans. TGS also inhibits elongation and...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_09609822_v20_n17_pR704_Allo |
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todo:paper_09609822_v20_n17_pR704_Allo2023-10-03T15:54:05Z Gene silencing: Small RNAs control RNA polymerase II elongation Alló, M. Kornblihtt, A.R. RNA polymerase II small interfering RNA animal article Caenorhabditis elegans enzymology gene silencing genetic transcription genetics metabolism physiology Animals Caenorhabditis elegans Gene Silencing RNA Polymerase II RNA, Small Interfering Transcription, Genetic Caenorhabditis elegans Mammalia Short interfering RNAs trigger histone silencing marks and stalling of RNA polymerase II at their genomic target sites through a mechanism termed transcriptional gene silencing (TGS). The Argonaute protein NRDE-3, along with NRDE-2, are needed for TGS in C. elegans. TGS also inhibits elongation and controls alternative splicing in mammalian cells. © 2010 Elsevier Ltd. All rights reserved. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_09609822_v20_n17_pR704_Allo |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
RNA polymerase II small interfering RNA animal article Caenorhabditis elegans enzymology gene silencing genetic transcription genetics metabolism physiology Animals Caenorhabditis elegans Gene Silencing RNA Polymerase II RNA, Small Interfering Transcription, Genetic Caenorhabditis elegans Mammalia |
| spellingShingle |
RNA polymerase II small interfering RNA animal article Caenorhabditis elegans enzymology gene silencing genetic transcription genetics metabolism physiology Animals Caenorhabditis elegans Gene Silencing RNA Polymerase II RNA, Small Interfering Transcription, Genetic Caenorhabditis elegans Mammalia Alló, M. Kornblihtt, A.R. Gene silencing: Small RNAs control RNA polymerase II elongation |
| topic_facet |
RNA polymerase II small interfering RNA animal article Caenorhabditis elegans enzymology gene silencing genetic transcription genetics metabolism physiology Animals Caenorhabditis elegans Gene Silencing RNA Polymerase II RNA, Small Interfering Transcription, Genetic Caenorhabditis elegans Mammalia |
| description |
Short interfering RNAs trigger histone silencing marks and stalling of RNA polymerase II at their genomic target sites through a mechanism termed transcriptional gene silencing (TGS). The Argonaute protein NRDE-3, along with NRDE-2, are needed for TGS in C. elegans. TGS also inhibits elongation and controls alternative splicing in mammalian cells. © 2010 Elsevier Ltd. All rights reserved. |
| format |
JOUR |
| author |
Alló, M. Kornblihtt, A.R. |
| author_facet |
Alló, M. Kornblihtt, A.R. |
| author_sort |
Alló, M. |
| title |
Gene silencing: Small RNAs control RNA polymerase II elongation |
| title_short |
Gene silencing: Small RNAs control RNA polymerase II elongation |
| title_full |
Gene silencing: Small RNAs control RNA polymerase II elongation |
| title_fullStr |
Gene silencing: Small RNAs control RNA polymerase II elongation |
| title_full_unstemmed |
Gene silencing: Small RNAs control RNA polymerase II elongation |
| title_sort |
gene silencing: small rnas control rna polymerase ii elongation |
| url |
http://hdl.handle.net/20.500.12110/paper_09609822_v20_n17_pR704_Allo |
| work_keys_str_mv |
AT allom genesilencingsmallrnascontrolrnapolymeraseiielongation AT kornblihttar genesilencingsmallrnascontrolrnapolymeraseiielongation |
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1807323777478950912 |