In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement
Cedrela tubiflora aqueous leaf extracts are capable of inhibiting in vitro the activity of some components of the mouse immune system related to inflammatory responses. A significant reduction in the phagocytic capability and respiratory burst response (61.5% and 57.6%, respectively) of murine perit...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_0951418X_v10_n1_p37_Benencia |
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todo:paper_0951418X_v10_n1_p37_Benencia2023-10-03T15:50:34Z In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement Benencia, F. Courrèges, M.C. Coulombié, F.C. Antiinflammatory activity Cedrela tubiflora aqueous extract Complement Macrophages Neutrophils cedrela tubiflora extract complement plant extract unclassified drug aerobic metabolism animal cell antiinflammatory activity article concentration response controlled study hemolysis mouse neutrophil nonhuman peritoneum macrophage phagocytosis plant leaf respiratory burst Cedrela tubiflora aqueous leaf extracts are capable of inhibiting in vitro the activity of some components of the mouse immune system related to inflammatory responses. A significant reduction in the phagocytic capability and respiratory burst response (61.5% and 57.6%, respectively) of murine peritoneal macrophages was observed when these cells were incubated for 24 h with medium containing 1 mg/mL extract. On the other hand, at a concentration of 4 mg/mL, the extract reduced significantly the phagocytic activity of mouse polymorphonuclear leukocytes (87.5%) without altering the oxidative metabolism of these cells. Finally, a concentration of 2 mg/mL was required to inhibit the haemolytic activity of both pathways of mouse complement. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_0951418X_v10_n1_p37_Benencia |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
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R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Antiinflammatory activity Cedrela tubiflora aqueous extract Complement Macrophages Neutrophils cedrela tubiflora extract complement plant extract unclassified drug aerobic metabolism animal cell antiinflammatory activity article concentration response controlled study hemolysis mouse neutrophil nonhuman peritoneum macrophage phagocytosis plant leaf respiratory burst |
| spellingShingle |
Antiinflammatory activity Cedrela tubiflora aqueous extract Complement Macrophages Neutrophils cedrela tubiflora extract complement plant extract unclassified drug aerobic metabolism animal cell antiinflammatory activity article concentration response controlled study hemolysis mouse neutrophil nonhuman peritoneum macrophage phagocytosis plant leaf respiratory burst Benencia, F. Courrèges, M.C. Coulombié, F.C. In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement |
| topic_facet |
Antiinflammatory activity Cedrela tubiflora aqueous extract Complement Macrophages Neutrophils cedrela tubiflora extract complement plant extract unclassified drug aerobic metabolism animal cell antiinflammatory activity article concentration response controlled study hemolysis mouse neutrophil nonhuman peritoneum macrophage phagocytosis plant leaf respiratory burst |
| description |
Cedrela tubiflora aqueous leaf extracts are capable of inhibiting in vitro the activity of some components of the mouse immune system related to inflammatory responses. A significant reduction in the phagocytic capability and respiratory burst response (61.5% and 57.6%, respectively) of murine peritoneal macrophages was observed when these cells were incubated for 24 h with medium containing 1 mg/mL extract. On the other hand, at a concentration of 4 mg/mL, the extract reduced significantly the phagocytic activity of mouse polymorphonuclear leukocytes (87.5%) without altering the oxidative metabolism of these cells. Finally, a concentration of 2 mg/mL was required to inhibit the haemolytic activity of both pathways of mouse complement. |
| format |
JOUR |
| author |
Benencia, F. Courrèges, M.C. Coulombié, F.C. |
| author_facet |
Benencia, F. Courrèges, M.C. Coulombié, F.C. |
| author_sort |
Benencia, F. |
| title |
In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement |
| title_short |
In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement |
| title_full |
In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement |
| title_fullStr |
In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement |
| title_full_unstemmed |
In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement |
| title_sort |
in vitro activities of cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement |
| url |
http://hdl.handle.net/20.500.12110/paper_0951418X_v10_n1_p37_Benencia |
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