Pallidotomy in Parkinson's disease improves single-joint, repetitive, ballistic movements, but fails to modify multijoint, repetitive, gestural movements
We studied 12 non-demented PD patients in on state before and 3 months after posteroventral pallidotomy (PVP), in order to evaluate the effects of surgery upon an unconstrained, multijoint skilled movement as well as a single joint, repetitive, ballistic movement. A Selspot II System was used for th...
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todo:paper_08853185_v18_n3_p280_Merello2023-10-03T15:40:44Z Pallidotomy in Parkinson's disease improves single-joint, repetitive, ballistic movements, but fails to modify multijoint, repetitive, gestural movements Merello, M. Balej, J. Leiguarda, R. Ballistic movements Gestural movements Parkinson's disease Posteroventral pallidotomy acceleration accuracy adult aged arm movement article basal ganglion camera clinical article controlled study dementia elbow female frontal lobe gesture human image reconstruction information processing joint function kinematics linear system male mathematical computing motor dysfunction pallidotomy parietal lobe Parkinson disease postoperative period preoperative evaluation priority journal repetitive strain injury sensorimotor function spatial discrimination three dimensional imaging time perception velocity wrist Dyskinesias Elbow Female Follow-Up Studies Gestures Globus Pallidus Humans Image Processing, Computer-Assisted Imaging, Three-Dimensional Joints Male Middle Aged Movement Parkinson Disease Psychomotor Performance Treatment Outcome Wrist Joint We studied 12 non-demented PD patients in on state before and 3 months after posteroventral pallidotomy (PVP), in order to evaluate the effects of surgery upon an unconstrained, multijoint skilled movement as well as a single joint, repetitive, ballistic movement. A Selspot II System was used for three-dimensional data acquisition, processing and reconstruction of limb trajectories. Specific wrist kinematic features of spatial accuracy (linearity and planarity), temporal attributes (acceleration and velocity), spatiotemporal relationships (velocity-curvature coupling), and joint kinematic variables (relationships between wrist and elbow velocities and relative arm angle amplitudes) for each cycle of movement were graphically and numerically analysed. QMC was applied to single joint, repetitive, ballistic movements. QMC significantly improved after PVP (P < 0.0006). However, wrist as well as joint kinematic variables of the gestural movements failed to change significantly after PVP. The lack of improvement of the kinematic abnormalities of the gestural movement in PD patients would indicate that they are unrelated to the basic motor deficit; most likely they are the result of a disruption of a complex of sensorimotor integration processes due to abnormal parietofrontal basal ganglia interaction. © 2002 Movement Disorder Society. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_08853185_v18_n3_p280_Merello |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Ballistic movements Gestural movements Parkinson's disease Posteroventral pallidotomy acceleration accuracy adult aged arm movement article basal ganglion camera clinical article controlled study dementia elbow female frontal lobe gesture human image reconstruction information processing joint function kinematics linear system male mathematical computing motor dysfunction pallidotomy parietal lobe Parkinson disease postoperative period preoperative evaluation priority journal repetitive strain injury sensorimotor function spatial discrimination three dimensional imaging time perception velocity wrist Dyskinesias Elbow Female Follow-Up Studies Gestures Globus Pallidus Humans Image Processing, Computer-Assisted Imaging, Three-Dimensional Joints Male Middle Aged Movement Parkinson Disease Psychomotor Performance Treatment Outcome Wrist Joint |
| spellingShingle |
Ballistic movements Gestural movements Parkinson's disease Posteroventral pallidotomy acceleration accuracy adult aged arm movement article basal ganglion camera clinical article controlled study dementia elbow female frontal lobe gesture human image reconstruction information processing joint function kinematics linear system male mathematical computing motor dysfunction pallidotomy parietal lobe Parkinson disease postoperative period preoperative evaluation priority journal repetitive strain injury sensorimotor function spatial discrimination three dimensional imaging time perception velocity wrist Dyskinesias Elbow Female Follow-Up Studies Gestures Globus Pallidus Humans Image Processing, Computer-Assisted Imaging, Three-Dimensional Joints Male Middle Aged Movement Parkinson Disease Psychomotor Performance Treatment Outcome Wrist Joint Merello, M. Balej, J. Leiguarda, R. Pallidotomy in Parkinson's disease improves single-joint, repetitive, ballistic movements, but fails to modify multijoint, repetitive, gestural movements |
| topic_facet |
Ballistic movements Gestural movements Parkinson's disease Posteroventral pallidotomy acceleration accuracy adult aged arm movement article basal ganglion camera clinical article controlled study dementia elbow female frontal lobe gesture human image reconstruction information processing joint function kinematics linear system male mathematical computing motor dysfunction pallidotomy parietal lobe Parkinson disease postoperative period preoperative evaluation priority journal repetitive strain injury sensorimotor function spatial discrimination three dimensional imaging time perception velocity wrist Dyskinesias Elbow Female Follow-Up Studies Gestures Globus Pallidus Humans Image Processing, Computer-Assisted Imaging, Three-Dimensional Joints Male Middle Aged Movement Parkinson Disease Psychomotor Performance Treatment Outcome Wrist Joint |
| description |
We studied 12 non-demented PD patients in on state before and 3 months after posteroventral pallidotomy (PVP), in order to evaluate the effects of surgery upon an unconstrained, multijoint skilled movement as well as a single joint, repetitive, ballistic movement. A Selspot II System was used for three-dimensional data acquisition, processing and reconstruction of limb trajectories. Specific wrist kinematic features of spatial accuracy (linearity and planarity), temporal attributes (acceleration and velocity), spatiotemporal relationships (velocity-curvature coupling), and joint kinematic variables (relationships between wrist and elbow velocities and relative arm angle amplitudes) for each cycle of movement were graphically and numerically analysed. QMC was applied to single joint, repetitive, ballistic movements. QMC significantly improved after PVP (P < 0.0006). However, wrist as well as joint kinematic variables of the gestural movements failed to change significantly after PVP. The lack of improvement of the kinematic abnormalities of the gestural movement in PD patients would indicate that they are unrelated to the basic motor deficit; most likely they are the result of a disruption of a complex of sensorimotor integration processes due to abnormal parietofrontal basal ganglia interaction. © 2002 Movement Disorder Society. |
| format |
JOUR |
| author |
Merello, M. Balej, J. Leiguarda, R. |
| author_facet |
Merello, M. Balej, J. Leiguarda, R. |
| author_sort |
Merello, M. |
| title |
Pallidotomy in Parkinson's disease improves single-joint, repetitive, ballistic movements, but fails to modify multijoint, repetitive, gestural movements |
| title_short |
Pallidotomy in Parkinson's disease improves single-joint, repetitive, ballistic movements, but fails to modify multijoint, repetitive, gestural movements |
| title_full |
Pallidotomy in Parkinson's disease improves single-joint, repetitive, ballistic movements, but fails to modify multijoint, repetitive, gestural movements |
| title_fullStr |
Pallidotomy in Parkinson's disease improves single-joint, repetitive, ballistic movements, but fails to modify multijoint, repetitive, gestural movements |
| title_full_unstemmed |
Pallidotomy in Parkinson's disease improves single-joint, repetitive, ballistic movements, but fails to modify multijoint, repetitive, gestural movements |
| title_sort |
pallidotomy in parkinson's disease improves single-joint, repetitive, ballistic movements, but fails to modify multijoint, repetitive, gestural movements |
| url |
http://hdl.handle.net/20.500.12110/paper_08853185_v18_n3_p280_Merello |
| work_keys_str_mv |
AT merellom pallidotomyinparkinsonsdiseaseimprovessinglejointrepetitiveballisticmovementsbutfailstomodifymultijointrepetitivegesturalmovements AT balejj pallidotomyinparkinsonsdiseaseimprovessinglejointrepetitiveballisticmovementsbutfailstomodifymultijointrepetitivegesturalmovements AT leiguardar pallidotomyinparkinsonsdiseaseimprovessinglejointrepetitiveballisticmovementsbutfailstomodifymultijointrepetitivegesturalmovements |
| _version_ |
1807323063272865792 |