Corticosteroid synthesis in the central nervous system

The possibility that adrenocorticosteroids might be synthesized in the central nervous system was assessed by RT-PCR using primers for the CYP11B1 gene which codes for 11β-hydroxylase, the enzyme responsible for corticosterone and cortisol formation in the zona fasciculata, incubation of minces of s...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Gomez-Sanchez, C.E., Zhou, M.Y., Cozza, E.N., Morita, H., Eddleman, F.C., Gomez-Sanchez, E.P.
Formato:	JOUR
Materias:	19 ethynyldeoxycorticosterone corticosterone dehydrocorticosterone steroid 11beta monooxygenase steroid 11beta monooxygenase inhibitor unclassified drug animal cell animal tissue blood pressure measurement central nervous system function conference paper dose response enzyme mechanism hypertension inhibition kinetics intracerebroventricular drug administration male nonhuman priority journal rat steroidogenesis tissue distribution
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_07435800_v22_n4_p463_GomezSanchez
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Corticosteroid synthesis in the central nervous system
por: Cozza, Eduardo Néstor
Publicado: (1996)

The effects of (+)-Gossypol on 11β-HSD and the concentration of corticosterone and dehydrocorticosterone in mice serum and tissues
por: Qiu, Xiangjun, et al.
Publicado: (2012)

Cortisol: A tool to study aldosterone biosynthesis in rats
por: Matkovic, L., et al.

Cortisol: A tool to study aldosterone biosynthesis in rats
Publicado: (1995)

Cortisol: A tool to study aldosterone biosynthesis in rats
Publicado: (1995)

21-hydroxy-6,19-oxidoprogesterone: A novel synthetic steroid with specific antiglucocorticoid properties in the rat
por: Vicent, Guillermo Pablo, et al.
Publicado: (1997)

21-hydroxy-6,19-oxidoprogesterone: A novel synthetic steroid with specific antiglucocorticoid properties in the rat
por: Vicent, G.P., et al.

Features of the shuttle pair 11β-hydroxyprogesterone-11- ketoprogesterone
por: Vicent, Guillermo Pablo, et al.
Publicado: (1997)

Features of the shuttle pair 11β-hydroxyprogesterone-11- ketoprogesterone
por: Galigniana, M.D., et al.

The Bidder's organ of the toad Rhinella arenarum (Amphibia, Anura). Presence of steroidogenic enzymes
por: Scaia, M.F., et al.

MDCK cells express serotonin-regulable 11β-hydroxysteroid dehydrogenase type 2
por: Zallocchi, Marisa Laura, et al.
Publicado: (2006)

MDCK cells express serotonin-regulable 11β-hydroxysteroid dehydrogenase type 2
por: Zallocchi, M.L., et al.
Publicado: (2006)

MDCK cells express serotonin-regulable 11β-hydroxysteroid dehydrogenase type 2
por: Zallocchi, M.L., et al.

MDCK cells express serotonin-regulable 11β-hydroxysteroid dehydrogenase type 2
por: Zallocchi, M.L., et al.
Publicado: (2006)

Human chorionic gonadotropin-induced spermiation in Bufo arenarum is not mediated by steroid biosynthesis
Publicado: (2000)

Human chorionic gonadotropin-induced spermiation in Bufo arenarum is not mediated by steroid biosynthesis
por: Pozzi, A.G., et al.

The Bidder's organ of the toad Rhinella arenarum (Amphibia, Anura). Presence of steroidogenic enzymes
por: Scaia, María Florencia, et al.
Publicado: (2011)

Regulation of the 11β-hydroxysteroid dehydrogenase in the rat adrenal: Decrease enzymatic activity induced by ACTH
por: Morita, H., et al.

Dissociation of glucocorticoid effects of C-21 steroids at high concentrations in thymocytes
por: Castillo, Marta Beatriz, et al.
Publicado: (1983)

Dissociation of glucocorticoid effects of C-21 steroids at high concentrations in thymocytes
por: Castillo, M.B., et al.

Inhibition of aldosterone formation by cortisol in rat adrenal mitochondria
por: Matkovic, L., et al.

Seasonal changes in the activity of cytochrome P450C17 from the testis of Bufo arenarum
por: Pozzi, Andrea Gabriela, et al.
Publicado: (2002)

Seasonal changes in the activity of cytochrome P450C17 from the testis of Bufo arenarum
por: Solari, J.J.F., et al.

Sodium-retaining activity of some natural and synthetic 21-deoxysteroids
por: Burton, G., et al.

Inhibition of aldosterone formation by cortisol in rat adrenal mitochondria
por: Cozza, Eduardo Néstor
Publicado: (1995)

Inhibition of aldosterone formation by cortisol in rat adrenal mitochondria
por: Cozza, Eduardo Néstor
Publicado: (1995)

Sodium-retaining activity of some natural and synthetic 21-deoxysteroids
Publicado: (1995)

Synthesis of C(1)-C(11) oxygen-bridged pregnanes
por: Veleiro, Adriana Silvia, et al.
Publicado: (2005)

Synthesis of C(1)-C(11) oxygen-bridged pregnanes
por: Veleiro, A.S., et al.

Steroid-dependent management of biological responses in the nervous system
Publicado: (2013)

Steroid-dependent management of biological responses in the nervous system
por: Galigniana, M.D.

Effect of stress on hepatic 11β-hydroxysteroid dehydrogenase activity and its influence on carbohydrate metabolism
por: Altuna, M.E., et al.

Two novel steroidal glycoside sulfates from the starfish cosmasterias lurida
por: Maier, Marta Silvia, et al.
Publicado: (1993)

Two novel steroidal glycoside sulfates from the starfish cosmasterias lurida
por: Maier, M.S., et al.

Effect of stress on hepatic 11β-hydroxysteroid dehydrogenase activity and its influence on carbohydrate metabolism
Publicado: (2006)

Differences in nuclear retention characteristics of agonist-activated glucocorticoid receptor may determine specific responses
por: Vicent, Guillermo Pablo, et al.
Publicado: (2002)

Differences in nuclear retention characteristics of agonist-activated glucocorticoid receptor may determine specific responses
por: Vicent, G.P., et al.

Effect of corticosteroids on proximal tubular acidification in the rat
Publicado: (1987)

Effect of corticosteroids on proximal tubular acidification in the rat
por: Damasco, M.C., et al.

The placenta as a glucocorticoid target tissue: Exchange assay of (3H)-dexamethasone binding and effect of steroids on receptor content
Publicado: (1983)