Cortisol: A tool to study aldosterone biosynthesis in rats

Corticosterone (B) and 18-hydroxy-11-deoxycorticosterone (18OHDOC) but not 11-deoxycorticosterone (DOC) displaced cortisol (F) specifically bound to rat adrenal mitochondria. F competitively inhibited aldosterone formation from B, 18OHB and 18OHDOC but did not inhibit conversions of DOC to B or 18OH...

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Detalles Bibliográficos
Autores principales:	Matkovic, L., Gomez-sanchez, C.E., Lantos, C.P., Cozza, E.N.
Formato:	JOUR
Materias:	18 hydroxydeoxycorticosterone aldosterone corticosterone cytochrome p450 deoxycorticosterone hydrocortisone steroid 11beta monooxygenase adrenal cortex animal tissue conference paper controlled study enzyme activity enzyme substrate male mitochondrion nonhuman priority journal rat steroidogenesis 18-Hydroxydesoxycorticosterone Adrenal Glands Aldosterone Animal Binding, Competitive Corticosterone Hydrocortisone Male Mitochondria Rats Rats, Inbred Strains Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S.
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_07435800_v21_n1-2_p471_Matkovic
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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