High δ-aminolevulinic acid uptake in rat cerebral cortex: effect on porphyrin biosynthesis

The response of nerve cells to high exogenous aminolevulinic acid (ALA) concentrations was studied by examining the changes in its uptake and in porphyrin biosynthesis. ALA was shown to be taken up by cerebral cortex particles by a non-saturable process. As opposed to other previously described expe...

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Detalles Bibliográficos
Autores principales: Juknat, A.A., Kotler, M.L., del Carmen Batlle, A.M.
Formato: JOUR
Materias:
Acute porphyric attac
AIP brain tissue model
ALA accumulation
ALA uptake
Cerebral cortex particles
Glucose uptake
PBG accumulation
Porphyrin biosynthesis
aminolevulinic acid
glucose
porphyrin
animal tissue
article
bioaccumulation
brain cortex
controlled study
male
nerve cell
nonhuman
porphyria
priority journal
protein synthesis
rat
Aminolevulinic Acid
Animal
Cerebral Cortex
Chromatography, High Pressure Liquid
Glucose
Heme
In Vitro
Male
Porphyrins
Rats
Spectrometry, Fluorescence
Support, Non-U.S. Gov't
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_07428413_v111_n1_p143_Juknat
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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