Cyclophosphamide and its metabolite acrolein. Some studies on their porphyrinogenic action in 17 day old chick embryo.

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1. Some studies of cyclophosphamide (CP) and its metabolite acrolein in chick embryo liver were carried out in order to investigate the mechanism of the porphyrinogenic action of CP. 2. In vitro and in vivo studies revealed that CP induced but did not activate delta-aminolaevulinic acid (ALA) syntha...

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Detalles Bibliográficos
Autores principales: Cochón, A.C., San Martín de Viale, L.C., Wainstok de Calmanovici, R.
Formato: JOUR
Lenguaje:English
Materias:
5 aminolevulinate synthase
acrolein
allylisopropylacetamide
cyclophosphamide
Cytochrome P 450 Enzyme System
cytochrome P450
phenobarbital
porphyrin
proadifen
animal
article
biosynthesis
chemical structure
chemistry
chick embryo
drug effect
enzyme induction
enzymology
gestational age
liver
metabolism
5-Aminolevulinate Synthetase
Acrolein
Allylisopropylacetamide
Animal
Chick Embryo
Cyclophosphamide
Cytochrome P-450 Enzyme System
Enzyme Induction
Gestational Age
Liver
Molecular Structure
Phenobarbital
Porphyrins
Proadifen
Support, Non-U.S. Gov't
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_07428413_v102_n1_p143_Cochon
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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