Regional differences in veins wall viscosity, compliance, energetics and damping: Analysis of the pressure-diameter relationship during cyclical overloads
Background: The characterization of the dynamic process of veins walls is essential to understand venous functioning under normal and pathological conditions. However, little work has been done on dynamic venous properties. Aim: To characterize vein compliance (C), viscosity (η), peak-strain (WSt) a...
Guardado en:
| Autores principales: | , , , |
|---|---|
| Formato: | JOUR |
| Lenguaje: | English |
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_07169760_v41_n2_p227_Zocalo |
| Aporte de: |
| id |
todo:paper_07169760_v41_n2_p227_Zocalo |
|---|---|
| record_format |
dspace |
| spelling |
todo:paper_07169760_v41_n2_p227_Zocalo2023-10-03T15:36:19Z Regional differences in veins wall viscosity, compliance, energetics and damping: Analysis of the pressure-diameter relationship during cyclical overloads Zócalo, Y. Santana, D.B. Lluberas, S. Armentano, R.L. Compliance Damping Energetic Vascular physiology Venous wall Viscosity animal tissue article bioenergy biomechanics blood vessel function cava vein femoral vein jugular vein mechanical stress nonhuman pressure volume curve sheep vein compliance vein diameter vein wall venous circulation viscosity Animals Biomechanics Blood Pressure Blood Volume Compliance Femoral Vein Jugular Veins Sheep Vena Cava, Inferior Viscosity Ovis aries Background: The characterization of the dynamic process of veins walls is essential to understand venous functioning under normal and pathological conditions. However, little work has been done on dynamic venous properties. Aim: To characterize vein compliance (C), viscosity (η), peak-strain (WSt) and dissipated (WD) energy, damping (ξ), and their regional differences in order to evaluate their role in venous functioning during volume-pressure overloads. Methods: In a mock circulation, pressure (P) and diameter (D) of different veins (anterior cava, jugular and femoral; from 7 sheep), were registered during cyclical volume-pressure pulses. From the P-D relationship, C, WSt and ξ (at low and high P-D levels), η and WD were calculated. Results: For each vein there were P-dependent differences in biomechanical, energetics, and damping capability. There were regional-differences in C, η, WSt and WD (p<0.05), but not in ξ. Conclusion: The regional-dependent differences in dynamics and energetics, and regional-similitude in damping could be important to ensure venous functioning during acute overloads. The lower C and higher WSt and WD found in back-limb veins (femoral), commonly submitted to high volume-pressure loads (i.e. during walking), could be considered relevant to ensure adequate venous system functionality and venous wall protection simultaneously. JOUR English info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_07169760_v41_n2_p227_Zocalo |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| language |
English |
| orig_language_str_mv |
English |
| topic |
Compliance Damping Energetic Vascular physiology Venous wall Viscosity animal tissue article bioenergy biomechanics blood vessel function cava vein femoral vein jugular vein mechanical stress nonhuman pressure volume curve sheep vein compliance vein diameter vein wall venous circulation viscosity Animals Biomechanics Blood Pressure Blood Volume Compliance Femoral Vein Jugular Veins Sheep Vena Cava, Inferior Viscosity Ovis aries |
| spellingShingle |
Compliance Damping Energetic Vascular physiology Venous wall Viscosity animal tissue article bioenergy biomechanics blood vessel function cava vein femoral vein jugular vein mechanical stress nonhuman pressure volume curve sheep vein compliance vein diameter vein wall venous circulation viscosity Animals Biomechanics Blood Pressure Blood Volume Compliance Femoral Vein Jugular Veins Sheep Vena Cava, Inferior Viscosity Ovis aries Zócalo, Y. Santana, D.B. Lluberas, S. Armentano, R.L. Regional differences in veins wall viscosity, compliance, energetics and damping: Analysis of the pressure-diameter relationship during cyclical overloads |
| topic_facet |
Compliance Damping Energetic Vascular physiology Venous wall Viscosity animal tissue article bioenergy biomechanics blood vessel function cava vein femoral vein jugular vein mechanical stress nonhuman pressure volume curve sheep vein compliance vein diameter vein wall venous circulation viscosity Animals Biomechanics Blood Pressure Blood Volume Compliance Femoral Vein Jugular Veins Sheep Vena Cava, Inferior Viscosity Ovis aries |
| description |
Background: The characterization of the dynamic process of veins walls is essential to understand venous functioning under normal and pathological conditions. However, little work has been done on dynamic venous properties. Aim: To characterize vein compliance (C), viscosity (η), peak-strain (WSt) and dissipated (WD) energy, damping (ξ), and their regional differences in order to evaluate their role in venous functioning during volume-pressure overloads. Methods: In a mock circulation, pressure (P) and diameter (D) of different veins (anterior cava, jugular and femoral; from 7 sheep), were registered during cyclical volume-pressure pulses. From the P-D relationship, C, WSt and ξ (at low and high P-D levels), η and WD were calculated. Results: For each vein there were P-dependent differences in biomechanical, energetics, and damping capability. There were regional-differences in C, η, WSt and WD (p<0.05), but not in ξ. Conclusion: The regional-dependent differences in dynamics and energetics, and regional-similitude in damping could be important to ensure venous functioning during acute overloads. The lower C and higher WSt and WD found in back-limb veins (femoral), commonly submitted to high volume-pressure loads (i.e. during walking), could be considered relevant to ensure adequate venous system functionality and venous wall protection simultaneously. |
| format |
JOUR |
| author |
Zócalo, Y. Santana, D.B. Lluberas, S. Armentano, R.L. |
| author_facet |
Zócalo, Y. Santana, D.B. Lluberas, S. Armentano, R.L. |
| author_sort |
Zócalo, Y. |
| title |
Regional differences in veins wall viscosity, compliance, energetics and damping: Analysis of the pressure-diameter relationship during cyclical overloads |
| title_short |
Regional differences in veins wall viscosity, compliance, energetics and damping: Analysis of the pressure-diameter relationship during cyclical overloads |
| title_full |
Regional differences in veins wall viscosity, compliance, energetics and damping: Analysis of the pressure-diameter relationship during cyclical overloads |
| title_fullStr |
Regional differences in veins wall viscosity, compliance, energetics and damping: Analysis of the pressure-diameter relationship during cyclical overloads |
| title_full_unstemmed |
Regional differences in veins wall viscosity, compliance, energetics and damping: Analysis of the pressure-diameter relationship during cyclical overloads |
| title_sort |
regional differences in veins wall viscosity, compliance, energetics and damping: analysis of the pressure-diameter relationship during cyclical overloads |
| url |
http://hdl.handle.net/20.500.12110/paper_07169760_v41_n2_p227_Zocalo |
| work_keys_str_mv |
AT zocaloy regionaldifferencesinveinswallviscositycomplianceenergeticsanddampinganalysisofthepressurediameterrelationshipduringcyclicaloverloads AT santanadb regionaldifferencesinveinswallviscositycomplianceenergeticsanddampinganalysisofthepressurediameterrelationshipduringcyclicaloverloads AT lluberass regionaldifferencesinveinswallviscositycomplianceenergeticsanddampinganalysisofthepressurediameterrelationshipduringcyclicaloverloads AT armentanorl regionaldifferencesinveinswallviscositycomplianceenergeticsanddampinganalysisofthepressurediameterrelationshipduringcyclicaloverloads |
| _version_ |
1807320791246700544 |