Erythrocyte alkaline phosphatase in patients with myotonic muscle disorders.

The allosteric behaviour of the p-nitrophenyl-phosphatase (E.C.3.1.3.1.) from membrane erythrocytes was investigated in the following multisystemic diseases: myotonic dystrophy, limb-girdle muscular dystrophy, Charcot-Marie-Tooth and juvenile spinal muscular atrophy; in myotonia congenita, which is...

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Detalles Bibliográficos
Autores principales: Goldemberg, A.L., Madrid, E.A., García, A.M., Roubicek, M., Esteban Trucco, R.
Formato: JOUR
Lenguaje:English
Materias:
alkaline phosphatase
article
blood
enzymology
erythrocyte membrane
human
muscular dystrophy
neuromuscular disease
Alkaline Phosphatase
Erythrocyte Membrane
Humans
Muscular Dystrophies
Neuromuscular Diseases
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_05355133_v37_n4_p247_Goldemberg
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_05355133_v37_n4_p247_Goldemberg
record_format dspace
spelling todo:paper_05355133_v37_n4_p247_Goldemberg2023-10-03T15:34:12Z Erythrocyte alkaline phosphatase in patients with myotonic muscle disorders. Goldemberg, A.L. Madrid, E.A. García, A.M. Roubicek, M. Esteban Trucco, R. alkaline phosphatase article blood enzymology erythrocyte membrane human muscular dystrophy neuromuscular disease Alkaline Phosphatase Erythrocyte Membrane Humans Muscular Dystrophies Neuromuscular Diseases The allosteric behaviour of the p-nitrophenyl-phosphatase (E.C.3.1.3.1.) from membrane erythrocytes was investigated in the following multisystemic diseases: myotonic dystrophy, limb-girdle muscular dystrophy, Charcot-Marie-Tooth and juvenile spinal muscular atrophy; in myotonia congenita, which is not a multisystemic disease, and in healthy controls. The Hill coefficient in F inhibition in controls was different from that in multisystemic diseases patients but not from that in myotonia congenita patients. Changes in the cooperative type kinetics would suggest that the interaction membrane-enzyme in controls and in patients with neuromuscular disorders is only different for multisystemic diseases. Fil:Goldemberg, A.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR English info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_05355133_v37_n4_p247_Goldemberg
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
language English
orig_language_str_mv English
topic alkaline phosphatase
article
blood
enzymology
erythrocyte membrane
human
muscular dystrophy
neuromuscular disease
Alkaline Phosphatase
Erythrocyte Membrane
Humans
Muscular Dystrophies
Neuromuscular Diseases
spellingShingle alkaline phosphatase
article
blood
enzymology
erythrocyte membrane
human
muscular dystrophy
neuromuscular disease
Alkaline Phosphatase
Erythrocyte Membrane
Humans
Muscular Dystrophies
Neuromuscular Diseases
Goldemberg, A.L.
Madrid, E.A.
García, A.M.
Roubicek, M.
Esteban Trucco, R.
Erythrocyte alkaline phosphatase in patients with myotonic muscle disorders.
topic_facet alkaline phosphatase
article
blood
enzymology
erythrocyte membrane
human
muscular dystrophy
neuromuscular disease
Alkaline Phosphatase
Erythrocyte Membrane
Humans
Muscular Dystrophies
Neuromuscular Diseases
description The allosteric behaviour of the p-nitrophenyl-phosphatase (E.C.3.1.3.1.) from membrane erythrocytes was investigated in the following multisystemic diseases: myotonic dystrophy, limb-girdle muscular dystrophy, Charcot-Marie-Tooth and juvenile spinal muscular atrophy; in myotonia congenita, which is not a multisystemic disease, and in healthy controls. The Hill coefficient in F inhibition in controls was different from that in multisystemic diseases patients but not from that in myotonia congenita patients. Changes in the cooperative type kinetics would suggest that the interaction membrane-enzyme in controls and in patients with neuromuscular disorders is only different for multisystemic diseases.
format JOUR
author Goldemberg, A.L.
Madrid, E.A.
García, A.M.
Roubicek, M.
Esteban Trucco, R.
author_facet Goldemberg, A.L.
Madrid, E.A.
García, A.M.
Roubicek, M.
Esteban Trucco, R.
author_sort Goldemberg, A.L.
title Erythrocyte alkaline phosphatase in patients with myotonic muscle disorders.
title_short Erythrocyte alkaline phosphatase in patients with myotonic muscle disorders.
title_full Erythrocyte alkaline phosphatase in patients with myotonic muscle disorders.
title_fullStr Erythrocyte alkaline phosphatase in patients with myotonic muscle disorders.
title_full_unstemmed Erythrocyte alkaline phosphatase in patients with myotonic muscle disorders.
title_sort erythrocyte alkaline phosphatase in patients with myotonic muscle disorders.
url http://hdl.handle.net/20.500.12110/paper_05355133_v37_n4_p247_Goldemberg
work_keys_str_mv AT goldembergal erythrocytealkalinephosphataseinpatientswithmyotonicmuscledisorders
AT madridea erythrocytealkalinephosphataseinpatientswithmyotonicmuscledisorders
AT garciaam erythrocytealkalinephosphataseinpatientswithmyotonicmuscledisorders
AT roubicekm erythrocytealkalinephosphataseinpatientswithmyotonicmuscledisorders
AT estebantruccor erythrocytealkalinephosphataseinpatientswithmyotonicmuscledisorders
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