Alkaloids of Datura ferox from Argentina

Chromatographic procedures (HPLC, GC-MS) are outlined in this paper for the analysis of alkaloids in poisonous Datura ferox seeds of Argentina, from which previously only quantitative analysis for scopolamine was known. Five additional tropane alkaloids are now identified as 3α-tigloyloxytropane (ti...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Vitale, A.A., Acher, A., Pomilio, A.B.
Formato: JOUR
Materias:
3-Phenylacetoxy-6β,7β-epoxytropane (3-phenylacetoxyscopine)
3α-Tigloyloxytropane (tigloyltropeine)
7β-Hydroxy-6β-isovaleroyloxy-3α-tigloyloxytropane
7β-Hydroxy-6β-propenyloxy-3α-tropoyloxytropane
Aposcopolamine (apohyoscine)
Datura ferox
GC-MS
HPLC
Hygrine
Scopolamine (hyoscine)
Tropane alkaloids
hyoscyamine
nicotine
plant extract
scopolamine
tropane alkaloid
tropane derivative
argentina
article
drug determination
drug isolation
drug structure
drug toxicity
gas chromatography
high performance liquid chromatography
mass spectrometry
nonhuman
plant seed
Alkaloids
Argentina
Chromatography, High Pressure Liquid
Humans
Plant Extracts
Seeds
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03788741_v49_n2_p81_Vitale
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_03788741_v49_n2_p81_Vitale
record_format dspace
spelling todo:paper_03788741_v49_n2_p81_Vitale2023-10-03T15:33:20Z Alkaloids of Datura ferox from Argentina Vitale, A.A. Acher, A. Pomilio, A.B. 3-Phenylacetoxy-6β,7β-epoxytropane (3-phenylacetoxyscopine) 3α-Tigloyloxytropane (tigloyltropeine) 7β-Hydroxy-6β-isovaleroyloxy-3α-tigloyloxytropane 7β-Hydroxy-6β-propenyloxy-3α-tropoyloxytropane Aposcopolamine (apohyoscine) Datura ferox GC-MS HPLC Hygrine Scopolamine (hyoscine) Tropane alkaloids hyoscyamine nicotine plant extract scopolamine tropane alkaloid tropane derivative argentina article drug determination drug isolation drug structure drug toxicity gas chromatography high performance liquid chromatography mass spectrometry nonhuman plant seed Alkaloids Argentina Chromatography, High Pressure Liquid Humans Plant Extracts Seeds Chromatographic procedures (HPLC, GC-MS) are outlined in this paper for the analysis of alkaloids in poisonous Datura ferox seeds of Argentina, from which previously only quantitative analysis for scopolamine was known. Five additional tropane alkaloids are now identified as 3α-tigloyloxytropane (tigloyltropeine), 3-phenylacetoxy-6β,7β-epoxytropane (3-phenylacetoxyscopine), aposcopolamine (apohyoscine), 7β-hydroxy-6β-propenyloxy-3α-tropoyloxytropane, traces of 7β-hydroxy-6β-isovaleroyloxy-3α-tigloyloxytropane and a pyrrolidine alkaloid, hygrine. Two new structures, 3-phenylacetoxy-6β,7β-epoxytropane (3-phenylacetoxyscopine) and 7β-hydroxy-6β-propenyloxy-3α-tropoyloxytropane, are proposed on the basis of their spectra. Hyoscyamine, nicotine and tropane N-oxides were not detected in all samples studied. © 1995. Fil:Vitale, A.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Acher, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Pomilio, A.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03788741_v49_n2_p81_Vitale
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic 3-Phenylacetoxy-6β,7β-epoxytropane (3-phenylacetoxyscopine)
3α-Tigloyloxytropane (tigloyltropeine)
7β-Hydroxy-6β-isovaleroyloxy-3α-tigloyloxytropane
7β-Hydroxy-6β-propenyloxy-3α-tropoyloxytropane
Aposcopolamine (apohyoscine)
Datura ferox
GC-MS
HPLC
Hygrine
Scopolamine (hyoscine)
Tropane alkaloids
hyoscyamine
nicotine
plant extract
scopolamine
tropane alkaloid
tropane derivative
argentina
article
drug determination
drug isolation
drug structure
drug toxicity
gas chromatography
high performance liquid chromatography
mass spectrometry
nonhuman
plant seed
Alkaloids
Argentina
Chromatography, High Pressure Liquid
Humans
Plant Extracts
Seeds
spellingShingle 3-Phenylacetoxy-6β,7β-epoxytropane (3-phenylacetoxyscopine)
3α-Tigloyloxytropane (tigloyltropeine)
7β-Hydroxy-6β-isovaleroyloxy-3α-tigloyloxytropane
7β-Hydroxy-6β-propenyloxy-3α-tropoyloxytropane
Aposcopolamine (apohyoscine)
Datura ferox
GC-MS
HPLC
Hygrine
Scopolamine (hyoscine)
Tropane alkaloids
hyoscyamine
nicotine
plant extract
scopolamine
tropane alkaloid
tropane derivative
argentina
article
drug determination
drug isolation
drug structure
drug toxicity
gas chromatography
high performance liquid chromatography
mass spectrometry
nonhuman
plant seed
Alkaloids
Argentina
Chromatography, High Pressure Liquid
Humans
Plant Extracts
Seeds
Vitale, A.A.
Acher, A.
Pomilio, A.B.
Alkaloids of Datura ferox from Argentina
topic_facet 3-Phenylacetoxy-6β,7β-epoxytropane (3-phenylacetoxyscopine)
3α-Tigloyloxytropane (tigloyltropeine)
7β-Hydroxy-6β-isovaleroyloxy-3α-tigloyloxytropane
7β-Hydroxy-6β-propenyloxy-3α-tropoyloxytropane
Aposcopolamine (apohyoscine)
Datura ferox
GC-MS
HPLC
Hygrine
Scopolamine (hyoscine)
Tropane alkaloids
hyoscyamine
nicotine
plant extract
scopolamine
tropane alkaloid
tropane derivative
argentina
article
drug determination
drug isolation
drug structure
drug toxicity
gas chromatography
high performance liquid chromatography
mass spectrometry
nonhuman
plant seed
Alkaloids
Argentina
Chromatography, High Pressure Liquid
Humans
Plant Extracts
Seeds
description Chromatographic procedures (HPLC, GC-MS) are outlined in this paper for the analysis of alkaloids in poisonous Datura ferox seeds of Argentina, from which previously only quantitative analysis for scopolamine was known. Five additional tropane alkaloids are now identified as 3α-tigloyloxytropane (tigloyltropeine), 3-phenylacetoxy-6β,7β-epoxytropane (3-phenylacetoxyscopine), aposcopolamine (apohyoscine), 7β-hydroxy-6β-propenyloxy-3α-tropoyloxytropane, traces of 7β-hydroxy-6β-isovaleroyloxy-3α-tigloyloxytropane and a pyrrolidine alkaloid, hygrine. Two new structures, 3-phenylacetoxy-6β,7β-epoxytropane (3-phenylacetoxyscopine) and 7β-hydroxy-6β-propenyloxy-3α-tropoyloxytropane, are proposed on the basis of their spectra. Hyoscyamine, nicotine and tropane N-oxides were not detected in all samples studied. © 1995.
format JOUR
author Vitale, A.A.
Acher, A.
Pomilio, A.B.
author_facet Vitale, A.A.
Acher, A.
Pomilio, A.B.
author_sort Vitale, A.A.
title Alkaloids of Datura ferox from Argentina
title_short Alkaloids of Datura ferox from Argentina
title_full Alkaloids of Datura ferox from Argentina
title_fullStr Alkaloids of Datura ferox from Argentina
title_full_unstemmed Alkaloids of Datura ferox from Argentina
title_sort alkaloids of datura ferox from argentina
url http://hdl.handle.net/20.500.12110/paper_03788741_v49_n2_p81_Vitale
work_keys_str_mv AT vitaleaa alkaloidsofdaturaferoxfromargentina
AT achera alkaloidsofdaturaferoxfromargentina
AT pomilioab alkaloidsofdaturaferoxfromargentina
_version_ 1807323656261468160

Ejemplares similares