A simple preparation ofan 18-oxygenated pregnane

Reductive oxygenation of (20R)-3β,20-diacetoxy-18-iodo-5-pregnene allowed the substitution of the neopentylic iodine at position 18 by a hydroxyl group, in high yield. Partial acetate migration from C-20 to C-18 was observed. Evidence is presented, which indicates that this migration occurs after fo...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Nicoletti, D., Ghini, A.A., Burton, G.
Formato:	JOUR
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03650375_v86_n3-6_p336_Nicoletti
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

A simple preparation ofan 18-oxygenated pregnane
Publicado: (1998)

Microwave assisted preparation of C(1)-C(11) oxygen-bridged pregnanes
por: Alvarez, L.D., et al.

Microwave assisted preparation of C(1)-C(11) oxygen-bridged pregnanes
por: Alvarez, Lautaro Damián, et al.
Publicado: (2011)

Simple synthetic approach to 6-oxa steroids. Synthesis of 6-oxa-5β-pregnane-3,20-dione
por: Nicoletti, D., et al.

Synthesis of C(1)-C(11) oxygen-bridged pregnanes
por: Veleiro, A.S., et al.

Arist�ofanes : Nubes /
por: Vel�asquez, �Oscar
Publicado: (2005)

Oxidative cyclization of iodo ketones. Synthesis of 6-oxa-5α-pregnane-3,20-dione
por: Nicoletti, D., et al.

An efficient enzymatic preparation of 20-pregnane succinates: chemoenzymatic synthesis of 20β-hemisuccinyloxy-5αH-pregnan-3-one
por: Monsalve, L.N., et al.

Synthesis of C(1)-C(11) oxygen-bridged pregnanes
por: Veleiro, Adriana Silvia, et al.
Publicado: (2005)

An efficient enzymatic preparation of 20-pregnane succinates: chemoenzymatic synthesis of 20β-hemisuccinyloxy-5αH-pregnan-3-one
por: Monsalve, Leandro Nicolás, et al.
Publicado: (2008)

Ring expansion of fused cyclopropylketones. Synthesis of a 12(13→18)-abeo-pregnane
por: Ferrara, A., et al.

Synthesis of 6,19-sulfamidate bridged pregnanes
por: Duran, F.J., et al.

Synthesis of 6,19-sulfamidate bridged pregnanes
por: Durán, Fernando Javier, et al.
Publicado: (2005)

Photooxygenation of pregnanes
por: Ponce, M.A., et al.

Ring expansion of fused cyclopropylketones. Synthesis of a 12(13→18)-abeo-pregnane
por: Ferrara, Andrés, et al.
Publicado: (1996)

Photooxygenation of pregnanes
Publicado: (2004)

A pregnane structurally related to withanolides from Physalis viscosa
por: Silva, G.L., et al.

A pregnane structurally related to withanolides from Physalis viscosa
por: Veleiro, Adriana Silvia, et al.
Publicado: (1993)

Preparation of 3β -Acetoxy-5β-pregnan-20-one from 3 a- Acetoxy-5β-cholan-24-oic Acid Aimed at the Isotopic Labelling of the Pregnane Side Chain
por: Deluca, M.E., et al.

Simple procedures for the preparation of α,ω-hydroxyalkanethiols
por: Iglesias, L.E., et al.

A pregnane glycoside from the roots of Mandevilla pentlandiana
por: Cabrera, G., et al.

Preparation of 3β -Acetoxy-5β-pregnan-20-one from 3 a- Acetoxy-5β-cholan-24-oic Acid Aimed at the Isotopic Labelling of the Pregnane Side Chain
por: Deluca, Mónica Eva, et al.
Publicado: (1984)

Rearrangement of 18-iodo- and 20-iodopregnanes mediated by iodosyl derivatives
por: Nicoletti, D., et al.

S�ocrates como chivo expiatorio o sobre la identificaci�on de Arist�ofanes y S�ocrates /
por: Cavallero, Pablo A.
Publicado: (2007)

Simple procedures for the preparation of α,ω-hydroxyalkanethiols
por: Iglesias, Luis Emilio, et al.
Publicado: (1996)

PhI=NSes mediated aziridination of 11-pregnane derivatives: Synthesis of an 11,12-aziridino analogue of neuroactive steroids
por: Di Chenna, Pablo Héctor, et al.
Publicado: (2003)

Neuroprotective action of synthetic steroids with oxygen bridge. Activity on GABAA receptor
por: Rey, M., et al.

A pregnane glycoside from the roots of Mandevilla pentlandiana
por: Cabrera, Gabriela Myriam, et al.
Publicado: (1992)

Simple synthetic approach to 6-oxa steroids. Synthesis of 6-oxa-5β-pregnane-3,20-dione
Publicado: (1995)

Synthesis of oxido-bridged analogs of 18-hydroxyprogesterone
por: Benedetti Doctorovich, M.O.V., et al.

PhI=NSes mediated aziridination of 11-pregnane derivatives: Synthesis of an 11,12-aziridino analogue of neuroactive steroids
por: Di Chenna, P.H., et al.

Rearrangement of 4β,5β-methylenepregnanes: A simple approach to A-homopregnanes and 5β-methylpregnanes
por: Di Chenna, P.H., et al.
Publicado: (2005)

Rearrangement of 4β,5β-methylenepregnanes: A simple approach to A-homopregnanes and 5β-methylpregnanes
por: Di Chenna, P.H., et al.

Rearrangement of 4β,5β-methylenepregnanes: A simple approach to A-homopregnanes and 5β-methylpregnanes
por: Di Chenna, P.H., et al.
Publicado: (2005)

Dipteran chromosomes: A simple method for obtaining high quality chromosomal preparations
por: Chirino, M.G., et al.

Lipase-catalysed deacetylation of androstane and pregnane derivatives: Influence of ring D substitution
por: Bruttomesso, A.C., et al.

A Facile One-pot Method for the Preparation of N-Alkylanilines
por: Vitale, A.A., et al.

Dipteran chromosomes: A simple method for obtaining high quality chromosomal preparations
por: Rossi, Luis Francisco, et al.
Publicado: (2014)

A convenient preparation of α,α-diphenylacetophenone
por: Nudelman, N.S., et al.

A simple enzymatic preparation of 2',3'-di-O-acetylnucleosides through a lipase catalyzed alcoholysis
por: Zinni, A., et al.