A simple preparation ofan 18-oxygenated pregnane
Reductive oxygenation of (20R)-3β,20-diacetoxy-18-iodo-5-pregnene allowed the substitution of the neopentylic iodine at position 18 by a hydroxyl group, in high yield. Partial acetate migration from C-20 to C-18 was observed. Evidence is presented, which indicates that this migration occurs after fo...
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| Formato: | JOUR |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_03650375_v86_n3-6_p336_Nicoletti |
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todo:paper_03650375_v86_n3-6_p336_Nicoletti2023-10-03T15:27:55Z A simple preparation ofan 18-oxygenated pregnane Nicoletti, D. Ghini, A.A. Burton, G. Reductive oxygenation of (20R)-3β,20-diacetoxy-18-iodo-5-pregnene allowed the substitution of the neopentylic iodine at position 18 by a hydroxyl group, in high yield. Partial acetate migration from C-20 to C-18 was observed. Evidence is presented, which indicates that this migration occurs after formation of the 18-alcohol. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03650375_v86_n3-6_p336_Nicoletti |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| description |
Reductive oxygenation of (20R)-3β,20-diacetoxy-18-iodo-5-pregnene allowed the substitution of the neopentylic iodine at position 18 by a hydroxyl group, in high yield. Partial acetate migration from C-20 to C-18 was observed. Evidence is presented, which indicates that this migration occurs after formation of the 18-alcohol. |
| format |
JOUR |
| author |
Nicoletti, D. Ghini, A.A. Burton, G. |
| spellingShingle |
Nicoletti, D. Ghini, A.A. Burton, G. A simple preparation ofan 18-oxygenated pregnane |
| author_facet |
Nicoletti, D. Ghini, A.A. Burton, G. |
| author_sort |
Nicoletti, D. |
| title |
A simple preparation ofan 18-oxygenated pregnane |
| title_short |
A simple preparation ofan 18-oxygenated pregnane |
| title_full |
A simple preparation ofan 18-oxygenated pregnane |
| title_fullStr |
A simple preparation ofan 18-oxygenated pregnane |
| title_full_unstemmed |
A simple preparation ofan 18-oxygenated pregnane |
| title_sort |
simple preparation ofan 18-oxygenated pregnane |
| url |
http://hdl.handle.net/20.500.12110/paper_03650375_v86_n3-6_p336_Nicoletti |
| work_keys_str_mv |
AT nicolettid asimplepreparationofan18oxygenatedpregnane AT ghiniaa asimplepreparationofan18oxygenatedpregnane AT burtong asimplepreparationofan18oxygenatedpregnane AT nicolettid simplepreparationofan18oxygenatedpregnane AT ghiniaa simplepreparationofan18oxygenatedpregnane AT burtong simplepreparationofan18oxygenatedpregnane |
| _version_ |
1807323889216258048 |