Alternative synthesis of (24S)-homoethylcastasterone from stigmasterol
24(S)-Homoethylcastasterone belongs to the group of natural products named brassinosteroids. This work reports its synthesis from stigmasterol through a new pathway which involves a reductive opening of a 5β,6β-steroidal epoxide derivative. Key intermediate compound 4a also allows to develop pathway...
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| Autores principales: | , |
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| Formato: | JOUR |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_03650375_v86_n3-6_p104_TemeCenturion |
| Aporte de: |
| Sumario: | 24(S)-Homoethylcastasterone belongs to the group of natural products named brassinosteroids. This work reports its synthesis from stigmasterol through a new pathway which involves a reductive opening of a 5β,6β-steroidal epoxide derivative. Key intermediate compound 4a also allows to develop pathways for the synthesis of highly active C-3 natural oxygenated brassinosteroids. |
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