Efectos de la concanavalina a sobre los embriones de Bufo arenarum
A study of the influence of the lectin Concanavalin A (Con A) on the development of Bufo arenarum was carried out. Two effects were observed: one on the embryo (growth inhibition and malformations appearance), and the other one, on the membrane covering the embryo (hatching inhibition). A direct act...
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| Autores principales: | , , , , |
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| Formato: | JOUR |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_03650375_v85_n1-2_p37_FernandezDeRecondo |
| Aporte de: |
| Sumario: | A study of the influence of the lectin Concanavalin A (Con A) on the development of Bufo arenarum was carried out. Two effects were observed: one on the embryo (growth inhibition and malformations appearance), and the other one, on the membrane covering the embryo (hatching inhibition). A direct action on the embryo seems to be discarded, because Con A does not cross the fertilization membrane, and -methyl mannoside reverses the effect very fast. Very probably the lectin recognizes and blocks glycosaminoglycans (GAGs) present on the fertilization membrane. The indol-HCl method for GAGs recognition was applied to an extract of membranes and results have shown that hyaluronic acid is probably involved in the observed effects. |
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