Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes
Biological and chemical characteristics of 99mTc‐phenethylamines complexes are presented. 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine, 2‐(3,4‐dimethoxyphenyl)ethylamine and 2‐(2‐amino‐4,5‐dimethoxyphenyl)‐ethylamine were used as ligands. A preliminary evaluation of these 99mTc‐complexes as dopamine re...
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todo:paper_03624803_v36_n6_p509_Vitale2023-10-03T15:27:07Z Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes Vitale, A.A. Calvino, M.A. Ferrari, C.C. Stahl, A.E. Pomilio, A.B. 2‐(2‐Amino‐4,5‐dimethoxyphenyl)ethylamine 2‐(3,4‐Dimethoxyphenyl)‐ethylamine 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine 99m‐Technetium complexes Biodistribution Preparation semiempirical ZINDO/1 calculations phenethylamine derivative technetium 99m technetium complex animal experiment article brain controlled study drug distribution drug structure drug synthesis electrophoresis female intracerebral drug administration isotope labeling nonhuman radiochromatography rat Animalia Biological and chemical characteristics of 99mTc‐phenethylamines complexes are presented. 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine, 2‐(3,4‐dimethoxyphenyl)ethylamine and 2‐(2‐amino‐4,5‐dimethoxyphenyl)‐ethylamine were used as ligands. A preliminary evaluation of these 99mTc‐complexes as dopamine receptor radioligands was also performed. Net charges at each atom were also calculated by a semiempirical ZINDO/1 method for comparison of free ligands' parameters with those of the respective technetium‐complexes. Copyright © 1995 John Wiley & Sons, Ltd. Fil:Vitale, A.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Calvino, M.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Ferrari, C.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Pomilio, A.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03624803_v36_n6_p509_Vitale |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
2‐(2‐Amino‐4,5‐dimethoxyphenyl)ethylamine 2‐(3,4‐Dimethoxyphenyl)‐ethylamine 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine 99m‐Technetium complexes Biodistribution Preparation semiempirical ZINDO/1 calculations phenethylamine derivative technetium 99m technetium complex animal experiment article brain controlled study drug distribution drug structure drug synthesis electrophoresis female intracerebral drug administration isotope labeling nonhuman radiochromatography rat Animalia |
spellingShingle |
2‐(2‐Amino‐4,5‐dimethoxyphenyl)ethylamine 2‐(3,4‐Dimethoxyphenyl)‐ethylamine 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine 99m‐Technetium complexes Biodistribution Preparation semiempirical ZINDO/1 calculations phenethylamine derivative technetium 99m technetium complex animal experiment article brain controlled study drug distribution drug structure drug synthesis electrophoresis female intracerebral drug administration isotope labeling nonhuman radiochromatography rat Animalia Vitale, A.A. Calvino, M.A. Ferrari, C.C. Stahl, A.E. Pomilio, A.B. Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes |
topic_facet |
2‐(2‐Amino‐4,5‐dimethoxyphenyl)ethylamine 2‐(3,4‐Dimethoxyphenyl)‐ethylamine 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine 99m‐Technetium complexes Biodistribution Preparation semiempirical ZINDO/1 calculations phenethylamine derivative technetium 99m technetium complex animal experiment article brain controlled study drug distribution drug structure drug synthesis electrophoresis female intracerebral drug administration isotope labeling nonhuman radiochromatography rat Animalia |
description |
Biological and chemical characteristics of 99mTc‐phenethylamines complexes are presented. 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine, 2‐(3,4‐dimethoxyphenyl)ethylamine and 2‐(2‐amino‐4,5‐dimethoxyphenyl)‐ethylamine were used as ligands. A preliminary evaluation of these 99mTc‐complexes as dopamine receptor radioligands was also performed. Net charges at each atom were also calculated by a semiempirical ZINDO/1 method for comparison of free ligands' parameters with those of the respective technetium‐complexes. Copyright © 1995 John Wiley & Sons, Ltd. |
format |
JOUR |
author |
Vitale, A.A. Calvino, M.A. Ferrari, C.C. Stahl, A.E. Pomilio, A.B. |
author_facet |
Vitale, A.A. Calvino, M.A. Ferrari, C.C. Stahl, A.E. Pomilio, A.B. |
author_sort |
Vitale, A.A. |
title |
Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes |
title_short |
Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes |
title_full |
Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes |
title_fullStr |
Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes |
title_full_unstemmed |
Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes |
title_sort |
preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes |
url |
http://hdl.handle.net/20.500.12110/paper_03624803_v36_n6_p509_Vitale |
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