Synthesis of [21‐13C]‐cholesterol
The synthesis of [21‐13C]‐cholesterol (5) from 3β‐O‐(t‐butyldimethylsilyl)‐17β‐cyano‐androst‐5‐ene (1) is described. Labelled carbon‐atom was introduced by Grignard reaction of nitrile derivative with [13C]‐methylmagnesium iodide. Location of label was confirmed by 13C‐NMR spectroscopy. Copyright ©...
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| Autores principales: | , |
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_03624803_v34_n2_p127_Caballero |
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| Sumario: | The synthesis of [21‐13C]‐cholesterol (5) from 3β‐O‐(t‐butyldimethylsilyl)‐17β‐cyano‐androst‐5‐ene (1) is described. Labelled carbon‐atom was introduced by Grignard reaction of nitrile derivative with [13C]‐methylmagnesium iodide. Location of label was confirmed by 13C‐NMR spectroscopy. Copyright © 1994 John Wiley & Sons, Ltd. |
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