Synthesis of [21‐13C]‐cholesterol

The synthesis of [21‐13C]‐cholesterol (5) from 3β‐O‐(t‐butyldimethylsilyl)‐17β‐cyano‐androst‐5‐ene (1) is described. Labelled carbon‐atom was introduced by Grignard reaction of nitrile derivative with [13C]‐methylmagnesium iodide. Location of label was confirmed by 13C‐NMR spectroscopy. Copyright ©...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Caballero, G.M., Gros, E.G.
Formato:	JOUR
Materias:	synthesis [21‐13C]‐cholesterol carbon 13 cholesterol article cholesterol synthesis controlled study isotope labeling
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03624803_v34_n2_p127_Caballero
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_03624803_v34_n2_p127_Caballero
record_format	dspace
spelling	todo:paper_03624803_v34_n2_p127_Caballero2023-10-03T15:27:07Z Synthesis of [21‐13C]‐cholesterol Caballero, G.M. Gros, E.G. synthesis [21‐13C]‐cholesterol carbon 13 cholesterol article cholesterol synthesis controlled study isotope labeling The synthesis of [21‐13C]‐cholesterol (5) from 3β‐O‐(t‐butyldimethylsilyl)‐17β‐cyano‐androst‐5‐ene (1) is described. Labelled carbon‐atom was introduced by Grignard reaction of nitrile derivative with [13C]‐methylmagnesium iodide. Location of label was confirmed by 13C‐NMR spectroscopy. Copyright © 1994 John Wiley & Sons, Ltd. Fil:Caballero, G.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Gros, E.G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03624803_v34_n2_p127_Caballero
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	synthesis [21‐13C]‐cholesterol carbon 13 cholesterol article cholesterol synthesis controlled study isotope labeling
spellingShingle	synthesis [21‐13C]‐cholesterol carbon 13 cholesterol article cholesterol synthesis controlled study isotope labeling Caballero, G.M. Gros, E.G. Synthesis of [21‐13C]‐cholesterol
topic_facet	synthesis [21‐13C]‐cholesterol carbon 13 cholesterol article cholesterol synthesis controlled study isotope labeling
description	The synthesis of [21‐13C]‐cholesterol (5) from 3β‐O‐(t‐butyldimethylsilyl)‐17β‐cyano‐androst‐5‐ene (1) is described. Labelled carbon‐atom was introduced by Grignard reaction of nitrile derivative with [13C]‐methylmagnesium iodide. Location of label was confirmed by 13C‐NMR spectroscopy. Copyright © 1994 John Wiley & Sons, Ltd.
format	JOUR
author	Caballero, G.M. Gros, E.G.
author_facet	Caballero, G.M. Gros, E.G.
author_sort	Caballero, G.M.
title	Synthesis of [21‐13C]‐cholesterol
title_short	Synthesis of [21‐13C]‐cholesterol
title_full	Synthesis of [21‐13C]‐cholesterol
title_fullStr	Synthesis of [21‐13C]‐cholesterol
title_full_unstemmed	Synthesis of [21‐13C]‐cholesterol
title_sort	synthesis of [21‐13c]‐cholesterol
url	http://hdl.handle.net/20.500.12110/paper_03624803_v34_n2_p127_Caballero
work_keys_str_mv	AT caballerogm synthesisof2113ccholesterol AT groseg synthesisof2113ccholesterol
_version_	1782030475870601216

Synthesis of [21‐13C]‐cholesterol

Ejemplares similares