Synthesis of [20,21‐13C2]‐pregnenolone

The synthesis of [20,21‐13C2]‐pregnenolone (7) from androst‐5‐en‐3β‐ol‐17‐one (1) is described. Labelled carbons were introduced by two procedures, namely, condensation of 1 with K13CN and Grignard reaction of nitrile derivative 5 with [13C]‐methylmagnesium iodide. Location of labels was confirmed b...

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Detalles Bibliográficos
Autores principales:	Caballero, G.M., Gros, E.G.
Formato:	JOUR
Materias:	synthesis [20,21‐13C2]‐pregnenolone carbon 13 pregnenolone article controlled study drug synthesis isotope labeling
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03624803_v33_n10_p907_Caballero
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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