Network interactions among sensory neurons in the leech
Interactions among mechanosensory neurons, sensitive to touch, pressure and nociceptive stimuli in the leech nervous system were studied in isolated ganglia and in body-wall preparations. Pairs of touch-pressure, touch-nociceptive and pressure-nociceptive neurons were tested by suprathreshold stimul...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_03407594_v189_n1_p59_Burgin |
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todo:paper_03407594_v189_n1_p59_Burgin2023-10-03T15:26:00Z Network interactions among sensory neurons in the leech Burgin, A.M. Szczupak, L. Distal inhibition Intersensory Peripheral stimulation Primary sensory neurons Sensory network animal article cell membrane potential classification comparative study leech mechanotransduction nerve cell inhibition nerve cell network physiology sensory nerve cell stimulation Animals Leeches Mechanotransduction, Cellular Membrane Potentials Nerve Net Neural Inhibition Neurons, Afferent Physical Stimulation Interactions among mechanosensory neurons, sensitive to touch, pressure and nociceptive stimuli in the leech nervous system were studied in isolated ganglia and in body-wall preparations. Pairs of touch-pressure, touch-nociceptive and pressure-nociceptive neurons were tested by suprathreshold stimulation of one neuron while recording the response of the other, in both directions. Pressure and nociceptive stimulation evoked depolarizing and hyperpolarizing responses in touch cells, mediated by interneurons. The relative expression of these responses depended on the stimulus duration. One or two pressure cell spikes produced, predominantly, a depolarization of the touch cells, and increasing number of spikes evoked a hyperpolarization. Nociceptive cells produced primarily the hyperpolarization of touch cells at any stimulus duration. When touch cells were induced to fire by injection of positive current into the soma, stimulation of pressure cells inhibited touch cell activity. However, when touch cells were induced to fire by peripheral stimulation, pressure cell activation failed to inhibit touch cell firing. The results suggest that excitation of pressure and nociceptive cells would not limit the responses of touch cells to peripheral stimuli, but would inhibit the firing of touch cells evoked by their central connectivity network. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03407594_v189_n1_p59_Burgin |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Distal inhibition Intersensory Peripheral stimulation Primary sensory neurons Sensory network animal article cell membrane potential classification comparative study leech mechanotransduction nerve cell inhibition nerve cell network physiology sensory nerve cell stimulation Animals Leeches Mechanotransduction, Cellular Membrane Potentials Nerve Net Neural Inhibition Neurons, Afferent Physical Stimulation |
| spellingShingle |
Distal inhibition Intersensory Peripheral stimulation Primary sensory neurons Sensory network animal article cell membrane potential classification comparative study leech mechanotransduction nerve cell inhibition nerve cell network physiology sensory nerve cell stimulation Animals Leeches Mechanotransduction, Cellular Membrane Potentials Nerve Net Neural Inhibition Neurons, Afferent Physical Stimulation Burgin, A.M. Szczupak, L. Network interactions among sensory neurons in the leech |
| topic_facet |
Distal inhibition Intersensory Peripheral stimulation Primary sensory neurons Sensory network animal article cell membrane potential classification comparative study leech mechanotransduction nerve cell inhibition nerve cell network physiology sensory nerve cell stimulation Animals Leeches Mechanotransduction, Cellular Membrane Potentials Nerve Net Neural Inhibition Neurons, Afferent Physical Stimulation |
| description |
Interactions among mechanosensory neurons, sensitive to touch, pressure and nociceptive stimuli in the leech nervous system were studied in isolated ganglia and in body-wall preparations. Pairs of touch-pressure, touch-nociceptive and pressure-nociceptive neurons were tested by suprathreshold stimulation of one neuron while recording the response of the other, in both directions. Pressure and nociceptive stimulation evoked depolarizing and hyperpolarizing responses in touch cells, mediated by interneurons. The relative expression of these responses depended on the stimulus duration. One or two pressure cell spikes produced, predominantly, a depolarization of the touch cells, and increasing number of spikes evoked a hyperpolarization. Nociceptive cells produced primarily the hyperpolarization of touch cells at any stimulus duration. When touch cells were induced to fire by injection of positive current into the soma, stimulation of pressure cells inhibited touch cell activity. However, when touch cells were induced to fire by peripheral stimulation, pressure cell activation failed to inhibit touch cell firing. The results suggest that excitation of pressure and nociceptive cells would not limit the responses of touch cells to peripheral stimuli, but would inhibit the firing of touch cells evoked by their central connectivity network. |
| format |
JOUR |
| author |
Burgin, A.M. Szczupak, L. |
| author_facet |
Burgin, A.M. Szczupak, L. |
| author_sort |
Burgin, A.M. |
| title |
Network interactions among sensory neurons in the leech |
| title_short |
Network interactions among sensory neurons in the leech |
| title_full |
Network interactions among sensory neurons in the leech |
| title_fullStr |
Network interactions among sensory neurons in the leech |
| title_full_unstemmed |
Network interactions among sensory neurons in the leech |
| title_sort |
network interactions among sensory neurons in the leech |
| url |
http://hdl.handle.net/20.500.12110/paper_03407594_v189_n1_p59_Burgin |
| work_keys_str_mv |
AT burginam networkinteractionsamongsensoryneuronsintheleech AT szczupakl networkinteractionsamongsensoryneuronsintheleech |
| _version_ |
1807320789740945408 |